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thyronamine

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Thyronamine is a type of decarboxylated and deiodinated metabolite of the thyroid hormones thyroxine (T4) and 3,5,3'-triiodothyronine (T3). The word thyronamine can refer to either the family of molecules, or the specific molecule from which they are derived.

Wikidata facts

Mass
229.110279
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chemical formula
C₁₄H₁₅NO₂
canonical SMILES
C1=CC(=CC=C1CCN)OC2=CC=C(C=C2)O
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Thyronamine
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Thyronamine is a type of decarboxylated and deiodinated metabolite of the thyroid hormones thyroxine (T4) and 3,5,3'-triiodothyronine (T3). The word thyronamine can refer to either the family of molecules, or the specific molecule from which they are derived.

==Types== The group includes: Thyronamine (T0AM) 3-Iodothyronamine (T1AM), which is the most notable one as it is a trace amine found in the nervous system. It is a possible candidate for the natural ligand of the trace amine-associated receptor TAAR1 (TAR1), an intracellular G protein-coupled receptor 3,5-Diiodothyronamine (T2AM) 3,5,3'-Triiodothyronamine (T3AM)

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