toloxatone
Sign in to saveToloxatone (Humoryl) is an antidepressant launched in 1984 in France by Sanofi Aventis for the treatment of depression. It was discontinued in 2002. It acts as a selective reversible inhibitor of MAO-A (RIMA).
Research
86 papers- [Toloxatone and depression].Acta psiquiatrica y psicologica de America latina · 1991
- Characterization of forced degradation products of toloxatone by LC-ESI-MS/MS.Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society · 2018
- Toloxatone pharmacokinetics in the plasma and cerebrospinal fluid of the rabbit.The Journal of pharmacy and pharmacology · 1992
- Pharmacokinetic and pharmacodynamic interaction between toloxatone, a new reversible monoamine oxidase-A inhibitor, and oral tyramine in healthy subjects.Clinical pharmacology and therapeutics · 1992
- Effect of acute ethanol administration on toloxatone pharmacokinetics in rabbits.Alcoholism, clinical and experimental research · 1999
via PubMed
Wikidata facts
- Subclass of
- primary alcohol
- Mass
- 207.089543
- Has use
- medication
Show 5 more facts
- chemical formula
- C₁₁H₁₃NO₃
- World Health Organisation international non-proprietary name
- toloxatone
- canonical SMILES
- CC1=CC(=CC=C1)N2CC(OC2=O)CO
- Commons category
- Toloxatone
- subject has role
- monoamine oxidase inhibitor
Sources (2)
via Wikidata · CC0
~1 min read
Encyclopedic overview
3 sectionsContents
- Synthesis
- See also
- References
Toloxatone (Humoryl) is an antidepressant launched in 1984 in France by Sanofi Aventis for the treatment of depression. It was discontinued in 2002. It acts as a selective reversible inhibitor of MAO-A (RIMA).
==Synthesis== 500px|class=skin-invert-image
Excerpted from Wikipedia’s “toloxatone” article, available under the CC BY-SA 4.0 licence.
Available in 14 languages
- Français
- 中文
- Italiano
- العربية
- Bahasa Indonesia
- Hungarian
- Polski
- Serbian
- Serbian (Latin)
- Svenska
- Tiếng Việt
- Türkçe
- فارسی
via Wikidata sitelinks · CC0