Structure via PubChem · Public domain (PubChem)
tricetin
Sign in to saveAlso known as 3',4',5,5',7-pentahydroxyflavone, 5,7-DIHYDROXY-2-(3,4,5-TRIHYDROXYPHENYL)-4H-CHROMEN-4-ONE
Tricetin is a flavone, a type of flavonoid. It is a rare aglycone found in the pollen of members of the Myrtaceae, subfamily Leptospermoideae, such as Eucalyptus globulus. This compound shows anticancer effects on human breast adenocarcinoma MCF-7 cells. Moreover. a potent anti-inflammatory effect of tricetin has also been demonstrated in a model of acute pancreatitis. This observation was explained by the compound's radical scavenging effects, its inhibitory effect on the DNA damage sensor enzyme poly (ADP-ribose) polymerase-1 (PARP1) and PARP1-mediated cell death and suppression of inflammat
In the Vinony graph
Vinony's link graph records 65 inbound references to tricetin, and connects out to Myrtaceae, digital object identifier and International Standard Serial Number.
Vinony files it under Chembox image size set, ECHA InfoCard ID from Wikidata and Flavones.
Vinony links it to 6 Wikipedia language editions.
Chemical data
- Formula
- C15H10O7
- Molecular weight
- 302.23 g/mol
- IUPAC name
- 5,7-dihydroxy-2-(3,4,5-trihydroxyphenyl)chromen-4-one
- SMILES
- C1=C(C=C(C(=C1O)O)O)C2=CC(=O)C3=C(C=C(C=C3O2)O)O
- InChIKey
- ARSRJFRKVXALTF-UHFFFAOYSA-N
- XLogP
- 1
- Polar surface area
- 127 Ų
- H-bond donors
- 5
- H-bond acceptors
- 7
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
- Molecule type
- Small molecule
via ChEMBL · EBI
Wikidata facts
- Subclass of
- flavone
- Mass
- 302.043
Show 5 more facts
- canonical SMILES
- C1=C(C=C(C(=C1O)O)O)C2=CC(=O)C3=C(C=C(C=C3O2)O)O
- chemical formula
- C₁₅H₁₀O₇
- found in taxon
- Larix sibirica
- has characteristic
- bitterness
- Commons category
- Tricetin
Sources (2)
via Wikidata · CC0
~1 min read
Encyclopedic overview
2 sectionsContents
- See also
- References
Tricetin is a flavone, a type of flavonoid. It is a rare aglycone found in the pollen of members of the Myrtaceae, subfamily Leptospermoideae, such as Eucalyptus globulus. This compound shows anticancer effects on human breast adenocarcinoma MCF-7 cells. Moreover. a potent anti-inflammatory effect of tricetin has also been demonstrated in a model of acute pancreatitis. This observation was explained by the compound's radical scavenging effects, its inhibitory effect on the DNA damage sensor enzyme poly (ADP-ribose) polymerase-1 (PARP1) and PARP1-mediated cell death and suppression of inflammatory gene expression.
== See also == Tricin synthase produces tricin or tricetin 3′,5′-dimethyl ether Tricetin 3′,4′,5′-O-trimethyltransferase
Excerpted from Wikipedia’s “tricetin” article, available under the CC BY-SA 4.0 licence.