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tropane

Structure via PubChem · Public domain (PubChem)

EntityQ410271· pop 26· linked from 847 articles

Also known as (1R,5S)-8-methyl-8-azabicyclo[3.2.1]octane

Tropane is a nitrogenous bicyclic organic compound. It is mainly known for the other alkaloids derived from it, which include atropine and cocaine, among others. Tropane alkaloids occur in plants of the families Erythroxylaceae (including coca) and Solanaceae (including mandrake, henbane, deadly nightshade, datura, potato, tomato).

Chemical data

Formula
C8H15N
Molecular weight
125.21 g/mol
IUPAC name
(1S,5R)-8-methyl-8-azabicyclo[3.2.1]octane
SMILES
CN1[C@@H]2CCC[C@H]1CC2
InChIKey
XLRPYZSEQKXZAA-OCAPTIKFSA-N
XLogP
1.7
Polar surface area
3.2 Ų
H-bond donors
0
H-bond acceptors
1
Formal charge
0

via PubChem

Wikidata facts

Mass
125.120449
Show 5 more facts
chemical formula
C₈H₁₅N
Commons category
Tropane
boiling point
163
canonical SMILES
CN1C2CCCC1CC2
isomeric SMILES
CN1[C@@H]2CCC[C@H]1CC2
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Article

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Contents
  • See also
  • References

Tropane is a nitrogenous bicyclic organic compound. It is mainly known for the other alkaloids derived from it, which include atropine and cocaine, among others. Tropane alkaloids occur in plants of the families Erythroxylaceae (including coca) and Solanaceae (including mandrake, henbane, deadly nightshade, datura, potato, tomato).

Structurally, tropane is cycloheptane with a nitrogen bridge between carbons 1 and 5 and an additional methyl group attached to the nitrogen. While carbons 1 and 5 are asymmetric carbons, tropane itself is optically inactive due to mirror symmetry.

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