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GeneQ18037724· pop 6· linked from 6 articles

Also known as MT-TRX, MTRX, TRX2, COXPD29, thioredoxin 2, TXN

Thioredoxin, mitochondrial also known as thioredoxin-2 is a protein that in humans is encoded by the TXN2 gene on chromosome 22. This nuclear gene encodes a mitochondrial member of the thioredoxin family, a group of small multifunctional redox-active proteins. The encoded protein may play important roles in the regulation of the mitochondrial membrane potential and in protection against oxidant-induced apoptosis.

Gene data

TXN2
Name
thioredoxin 2
Type
protein-coding
Aliases
COXPD29, MT-TRX, MTRX, TRX2, TXN

This nuclear gene encodes a mitochondrial member of the thioredoxin family, a group of small multifunctional redox-active proteins. The encoded protein may play important roles in the regulation of the mitochondrial membrane potential and in protection against oxidant-induced apoptosis. [provided by RefSeq, Jul 2008].

via MyGene.info

Wikidata facts

Image
Protein TXN2 PDB 1uvz.png
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HomoloGene ID
40849
cytogenetic location
22q12.3
Sources (3)

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~3 min read

Article

6 sections
Contents
  • Structure
  • Function
  • Clinical significance
  • Interactions
  • References
  • Further reading

Thioredoxin, mitochondrial also known as thioredoxin-2 is a protein that in humans is encoded by the TXN2 gene on chromosome 22. This nuclear gene encodes a mitochondrial member of the thioredoxin family, a group of small multifunctional redox-active proteins. The encoded protein may play important roles in the regulation of the mitochondrial membrane potential and in protection against oxidant-induced apoptosis.

==Structure==

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