UBE2N
Sign in to saveAlso known as HEL-S-71, UBC13, UBCHBEN; UBC13, UbcH-ben, UbcH13, ubiquitin conjugating enzyme E2 N, UBCHBEN
Ubiquitin-conjugating enzyme E2 N is a protein that in humans is encoded by the UBE2N gene.
Gene data
UBE2N- Name
- ubiquitin conjugating enzyme E2 N
- Type
- protein-coding
- Position
- 93,405,673–93,442,263 (−)
- Aliases
- HEL-S-71, UBC13, UBCHBEN, UBCHBEN; UBC13, UbcH-ben, UbcH13
- Ensembl
- ENSG00000177889
- RefSeq RNA
- NM_003348.4
- RefSeq protein
- NP_003339.1
The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. Studies in mouse suggest that this protein plays a role in DNA postreplication repair. [provided by RefSeq, Jul 2008].
Gene Ontology
Biological process
Molecular function
Pathways
via MyGene.info
Gene · Ensembl
ubiquitin conjugating enzyme E2 N
- Symbol
- UBE2N
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 12:93,405,673-93,442,263
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
- Image
- Protein UBE2N PDB 1j7d.png
Show 8 more facts
- HomoloGene ID
- 128406
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/7334
- genomic end
- 93441947
- genomic start
- 93799449
- chromosome
- human chromosome 12
- cytogenetic location
- 12q22
- expressed in
- myocardium
Sources (4)
via Wikidata · CC0
~1 min read
Encyclopedic overview
4 sectionsContents
- Function
- Interactions
- References
- Further reading
Ubiquitin-conjugating enzyme E2 N is a protein that in humans is encoded by the UBE2N gene.
== Function ==
Excerpted from Wikipedia’s “UBE2N” article, available under the CC BY-SA 4.0 licence.