vincamine
Sign in to saveAlso known as vincamidol, (+)-Vincamine, Methyl vincaminate, Pervincamine, Vinkametrin, Devinkan, Devincan, Angiopac
Vincamine is a monoterpenoid indole alkaloid found in the leaves of Vinca minor (lesser periwinkle), comprising about 25–65% of its indole alkaloids by weight. It can also be synthesized from related alkaloids.
Research
523 papers- Vincamine, from an antioxidant and a cerebral vasodilator to its anticancer potential.Bioorganic & medicinal chemistry · 2023
- Vincamine as an agonist of G-protein-coupled receptor 40 effectively ameliorates diabetic peripheral neuropathy in mice.Acta pharmacologica Sinica · 2023
- Vincamine ameliorates hepatic fibrosis via inhibiting S100A4-mediated farnesoid X receptor activation: based on liver microenvironment and enterohepatic circulation dependence.British journal of pharmacology · 2025
- Evaluation of vincamine against Acetylcholinesterase enzyme.Cellular and molecular biology (Noisy-le-Grand, France) · 2022
- Vincamine Mitigates Methotrexate-Induced Liver Fibrosis Model.The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology · 2025
via PubMed
Wikidata facts
- Mass
- 354.194
Show 4 more facts
- chemical formula
- C₂₁H₂₆N₂O₃
- canonical SMILES
- CCC12CCCN3C1C4=C(CC3)C5=CC=CC=C5N4C(C2)(C(=O)OC)O
- isomeric SMILES
- CC[C@@]12CCCN3[C@@H]1C4=C(CC3)C5=CC=CC=C5N4[C@](C2)(C(=O)OC)O
- Commons category
- Vincamine
Sources (2)
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Article
8 sectionsContents
- Uses
- Chemistry
- Synthesis
- Derivatives
- Research
- See also
- References
- External links
Vincamine is a monoterpenoid indole alkaloid found in the leaves of Vinca minor (lesser periwinkle), comprising about 25–65% of its indole alkaloids by weight. It can also be synthesized from related alkaloids.
==Uses== Vincamine is sold in Europe as a prescription medicine for the treatment of primary degenerative and vascular dementia. In the United States, it is permitted to be sold as a dietary supplement when labeled for use in adults for six months or less. Most common preparations are in the sustained release tablet forms.