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xenoestrogen

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Also known as environmental estrogen, xenoestrogens

Xenoestrogens are a type of xenohormone that imitates estrogen. They can be either synthetic or natural chemical compounds. Synthetic xenoestrogens include some widely used industrial compounds, such as PCBs, BPA, and phthalates, which have estrogenic effects on a living organism even though they differ chemically from the estrogenic substances produced internally by the endocrine system of any organism. Natural xenoestrogens include phytoestrogens which are plant-derived xenoestrogens. Because the primary route of exposure to these compounds is by consumption of phytoestrogenic plants, they a

~27 min read

Encyclopedic overview

24 sections
Contents
  • Mechanism of action
  • Effects
  • Impact
  • Precocious puberty
  • Thelarche in Puerto Rico
  • Tuscany precocious puberty cases
  • Dairy contamination
  • Fish contamination
  • Implications
  • In other animals
  • Common environmental estrogens
  • Atrazine
  • BPA
  • DDT
  • Dioxin
  • Endosulfan
  • Brominated flame retardants
  • PCBs
  • Phthalates
  • Zeranol
  • Miscellaneous
  • See also
  • References
  • External links

Xenoestrogens are a type of xenohormone that imitates estrogen. They can be either synthetic or natural chemical compounds. Synthetic xenoestrogens include some widely used industrial compounds, such as PCBs, BPA, and phthalates, which have estrogenic effects on a living organism even though they differ chemically from the estrogenic substances produced internally by the endocrine system of any organism. Natural xenoestrogens include phytoestrogens which are plant-derived xenoestrogens. Because the primary route of exposure to these compounds is by consumption of phytoestrogenic plants, they are sometimes called "dietary estrogens". Mycoestrogens, estrogenic substances from fungi, are another type of xenoestrogen that are also considered mycotoxins.

Xenoestrogens are clinically significant because they can mimic the effects of endogenous estrogen and thus have been implicated in precocious puberty and other disorders of the reproductive system.

Excerpted from Wikipedia’s “xenoestrogen” article, available under the CC BY-SA 4.0 licence.