ZFP91
Sign in to saveAlso known as DMS-8, DSM-8, PZF, ZFP-91, ZNF757, FKSG11, ZFP91 zinc finger protein, ZFP91 zinc finger protein, atypical E3 ubiquitin ligase
Zinc finger protein 91 homolog is a protein that in humans is encoded by the ZFP91 gene.
Gene data
ZFP91- Name
- ZFP91 zinc finger protein, atypical E3 ubiquitin ligase
- Type
- protein-coding
- Position
- 58,578,476–58,621,674 (+)
- Aliases
- DMS-8, DSM-8, DSM8, FKSG11, PZF, ZFP-91, ZNF757
- Ensembl
- ENSG00000186660
- RefSeq RNA
- NM_001197051.2, NM_053023.5
- RefSeq protein
- NP_001183980.1, NP_444251.1
The protein encoded by this gene is a member of the zinc finger family of proteins. The gene product contains C2H2-type domains, which are the classical zinc finger domains found in numerous nucleic acid-binding proteins. This protein functions as a regulator of the non-canonical NF-kappaB pathway in lymphotoxin-beta receptor signaling. Alternative splicing results in multiple transcript variants. A read-through transcript variant composed of ZFP91 and the downstream CNTF gene sequence has been identified, but it is thought to be non-coding. Read-through transcription of ZFP91 and CNTF has also been observed in mouse. A ZFP91-related pseudogene has also been identified on chromosome 2. [provided by RefSeq, Oct 2010].
Gene Ontology
Biological process
Molecular function
Cellular component
via MyGene.info
Gene · Ensembl
ZFP91 zinc finger protein, atypical E3 ubiquitin ligase
- Symbol
- ZFP91
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 11:58,578,476-58,621,674
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
Show 7 more facts
- HomoloGene ID
- 43144
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/80829
- genomic end
- 58621550
- genomic start
- 58579063
- chromosome
- human chromosome 11
- cytogenetic location
- 11q12.1
Sources (3)
via Wikidata · CC0
~1 min read
Encyclopedic overview
2 sectionsContents
- References
- Further reading
Zinc finger protein 91 homolog is a protein that in humans is encoded by the ZFP91 gene.
The protein encoded by this gene is a member of the zinc finger family of proteins. The gene product contains C2H2 type domains, which are the classical zinc finger domains found in numerous nucleic acid-binding proteins. In addition to the monocistronic transcript originating from this locus, a co-transcribed variant composed of ZFP91 and CNTF sequence has been identified. The monocistronic and co-transcribed variants encode distinct isoforms. The co-transcription of ZFP91 and CNTF has also been observed in mouse.
Excerpted from Wikipedia’s “ZFP91” article, available under the CC BY-SA 4.0 licence.