Also known as ZPA, Zp-2, zona pellucida glycoprotein 2, OOMD6
Zona pellucida sperm-binding protein 2 is a protein that in humans is encoded by the ZP2 gene.
Gene data
ZP2- Name
- zona pellucida glycoprotein 2
- Type
- protein-coding
- Aliases
- OOMD6, OZEMA6, ZPA, Zp-2
The zona pellucida is an extracellular matrix that surrounds the oocyte and early embryo. It is composed of three glycoproteins with various functions during fertilization and preimplantation development. The glycosylated mature peptide is one of the structural components of the zona pellucida and functions in secondary binding and penetration of acrosome-reacted spermatozoa. Female mice lacking this gene do not form a stable zona matrix and are sterile. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2014].
via MyGene.info
Gene · Ensembl
zona pellucida glycoprotein 2
- Symbol
- ZP2
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- Chr HG926_PATCH:21,141-38,201
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
Show 5 more facts
- HomoloGene ID
- 48194
- exact match
- identifiers.org/ncbigene/7783
- genomic start
- 21208773
- genomic end
- 21225831
- cytogenetic location
- 16p12.3-p12.2
Sources (4)
via Wikidata · CC0
~2 min read
Article
4 sectionsContents
- Function
- 3D structure
- References
- Further reading
Zona pellucida sperm-binding protein 2 is a protein that in humans is encoded by the ZP2 gene.
== Function ==