Structure via PubChem · Public domain (PubChem)
α-acetyldigoxin
Sign in to saveα-Acetyldigoxin is a cardiac glycoside found in plants of the genus Digitalis, including Digitalis lanata. It is an acetyl derivative of digoxin and an isomer of β-acetyldigoxin.
Chemical data
- Formula
- C43H66O15
- Molecular weight
- 823 g/mol
- IUPAC name
- [6-[6-[[6-[[12,14-dihydroxy-10,13-dimethyl-17-(5-oxo-2H-furan-3-yl)-1,2,3,4,5,6,7,8,9,11,12,15,16,17-tetradecahydrocyclopenta[a]phenanthren-3-yl]oxy]-4-hydroxyoxan-2-yl]methoxy]-4-hydroxy-2-methyloxan-3-yl]oxy-3-hydroxy-2-methyloxan-4-yl] acetate
- SMILES
- CC1C(C(CC(O1)OC2C(OC(CC2O)OCC3CC(CC(O3)OC4CCC5(C(C4)CCC6C5CC(C7(C6(CCC7C8=CC(=O)OC8)O)C)O)C)O)C)OC(=O)C)O
- InChIKey
- KIOXJNPWRPISHM-UHFFFAOYSA-N
- XLogP
- 1.6
- Polar surface area
- 209 Ų
- H-bond donors
- 5
- H-bond acceptors
- 15
- Formal charge
- 0
via PubChem
Wikidata facts
- Mass
- 822.440171412
Show 3 more facts
- found in taxon
- Digitalis purpurea
- canonical SMILES
- CC1C(C(CC(O1)OC2C(OC(CC2O)OCC3CC(CC(O3)OC4CCC5(C(C4)CCC6C5CC(C7(C6(CCC7C8=CC(=O)OC8)O)C)O)C)O)C)OC(=O)C)O
- chemical formula
- C₄₃H₆₆O₁₅
Sources (1)
via Wikidata · CC0
~1 min read
Encyclopedic overview
1 sectionsContents
- References
α-Acetyldigoxin is a cardiac glycoside found in plants of the genus Digitalis, including Digitalis lanata. It is an acetyl derivative of digoxin and an isomer of β-acetyldigoxin.
α-Acetyldigoxin increases the contractility of the heart by its positive inotropic effect on cardiac muscle. The effects of α-acetyldigoxin begin 3–4 hours after administration, and maximize after 6–8 hours. It is prescribed for congestive chronic cardiac failure class II, III and IV.
Excerpted from Wikipedia’s “α-acetyldigoxin” article, available under the CC BY-SA 4.0 licence.