Structure via PubChem · Public domain (PubChem)
bufotalin
Sign in to saveBufotalin is a cardiotoxic bufanolide steroid, cardiac glycoside analogue, secreted by a number of toad species. Bufotalin can be extracted from the skin parotoid glands of several types of toad.
Chemical data
- Formula
- C26H36O6
- Molecular weight
- 444.6 g/mol
- IUPAC name
- [(3S,5R,8R,9S,10S,13R,14S,16S,17R)-3,14-dihydroxy-10,13-dimethyl-17-(6-oxopyran-3-yl)-1,2,3,4,5,6,7,8,9,11,12,15,16,17-tetradecahydrocyclopenta[a]phenanthren-16-yl] acetate
- SMILES
- CC(=O)O[C@H]1C[C@@]2([C@@H]3CC[C@@H]4C[C@H](CC[C@@]4([C@H]3CC[C@@]2([C@H]1C5=COC(=O)C=C5)C)C)O)O
- InChIKey
- VOZHMAYHYHEWBW-NVOOAVKYSA-N
- XLogP
- 2.5
- Polar surface area
- 93.1 Ų
- H-bond donors
- 2
- H-bond acceptors
- 6
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
- Molecule type
- Small molecule
via ChEMBL · EBI
Wikidata facts
- Mass
- 444.251189
Show 5 more facts
- found in taxon
- Asiatic toad
- chemical formula
- C₂₆H₃₆O₆
- isomeric SMILES
- CC(=O)O[C@H]1C[C@@]2([C@@H]3CC[C@@H]4C[C@H](CC[C@@]4([C@H]3CC[C@@]2([C@H]1C5=COC(=O)C=C5)C)C)O)O
- canonical SMILES
- CC(=O)OC1CC2(C3CCC4CC(CCC4(C3CCC2(C1C5=COC(=O)C=C5)C)C)O)O
- Commons category
- Bufotalin
via Wikidata · CC0
~3 min read
Encyclopedic overview
7 sectionsContents
- Sources
- Traditional medicine
- Toxicity
- Pharmacology and mechanism of action
- Pharmacokinetics
- Chemical properties
- References
Bufotalin is a cardiotoxic bufanolide steroid, cardiac glycoside analogue, secreted by a number of toad species. Bufotalin can be extracted from the skin parotoid glands of several types of toad.
==Sources== Rhinella marina (Cane toad), Rhaebo guttatus (Smooth-sided toad), Bufo melanostictus (Asian toad), and Bufo bufo (common European toad) are sources of bufotalin.
Excerpted from Wikipedia’s “bufotalin” article, available under the CC BY-SA 4.0 licence.
Gallery (3)
Available in 9 languages
via Wikidata sitelinks · CC0