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streptolysin

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Streptolysins are two homogenous exotoxins from Streptococcus pyogenes. Types include streptolysin O (SLO; slo), which is oxygen-labile, and streptolysin S (SLS; sagA), which is oxygen-stable.

Key facts

Nonhuman protein.Name
Streptolysin S
Nonhuman protein.Symbol
sagA
Nonhuman protein.UniProt
Q1J7I0
Nonhuman protein.Organism
Streptococcus pyogenes serotype M4 (strain MGAS10750)

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Streptolysin O
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5 sections
Contents
  • Streptolysin O
  • Group A ''Streptococcus'' infections
  • Streptolysin S
  • Applications and Diagnostic Use of Streptolysin O (SLO)
  • References

Streptolysins are two homogenous exotoxins from Streptococcus pyogenes. Types include streptolysin O (SLO; slo), which is oxygen-labile, and streptolysin S (SLS; sagA), which is oxygen-stable.

SLO is part of the thiol-activated cytolysin family. It is hemolytically active only in a reversibly reduced state. It is antigenic, so its antibody antistreptolysin O can be detected in an antistreptolysin O titre.

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