ALDH1A1
Sign in to saveAlso known as ALDC, ALDH-E1, ALDH1, ALDH11, HEL-9, HEL-S-53e, HEL12, PUMB1
Aldehyde dehydrogenase 1 family, member A1, also known as ALDH1A1 or retinaldehyde dehydrogenase 1 (RALDH1), is an enzyme that is encoded by the ALDH1A1 gene.
Gene data
ALDH1A1- Name
- aldehyde dehydrogenase 1 family member A1
- Type
- protein-coding
- Position
- 72,887,945–73,080,453 (−)
- Aliases
- ALDC, ALDH-E1, ALDH1, ALDH11, HEL-9, HEL-S-53e, HEL12, PUMB1, RALDH1
- Ensembl
- ENSG00000165092
- RefSeq RNA
- NM_000689.5
- RefSeq protein
- NP_000680.2
The protein encoded by this gene belongs to the aldehyde dehydrogenase family. Aldehyde dehydrogenase is the next enzyme after alcohol dehydrogenase in the major pathway of alcohol metabolism. There are two major aldehyde dehydrogenase isozymes in the liver, cytosolic and mitochondrial, which are encoded by distinct genes, and can be distinguished by their electrophoretic mobility, kinetic properties, and subcellular localization. This gene encodes the cytosolic isozyme. Studies in mice show that through its role in retinol metabolism, this gene may also be involved in the regulation of the metabolic responses to high-fat diet. [provided by RefSeq, Mar 2011].
Gene Ontology
Biological process
Molecular function
Pathways
via MyGene.info
Gene · Ensembl
aldehyde dehydrogenase 1 family member A1
- Symbol
- ALDH1A1
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 9:72,887,945-73,080,453
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
~4 min read
Encyclopedic overview
8 sectionsContents
- Function
- Clinical significance
- Obesity
- Errors due to historical nomenclature
- Species-specific expression
- References
- External links
- Further reading
Aldehyde dehydrogenase 1 family, member A1, also known as ALDH1A1 or retinaldehyde dehydrogenase 1 (RALDH1), is an enzyme that is encoded by the ALDH1A1 gene.
== Function ==
Excerpted from Wikipedia’s “ALDH1A1” article, available under the CC BY-SA 4.0 licence.