Structure via PubChem · Public domain (PubChem)
alverine
Sign in to saveAlso known as phenopropamine, N-ethyl-3-phenyl-N-(3-phenylpropyl)-1-propanamine, N,N-bis(3-phenylpropyl)ethylamine, N-ethyl-3,3'-diphenyldipropylamine, bis(gamma-phenylpropyl)ethylamine, di(phenylpropyl)ethylamine, N-ethyl-N-(3-phenylpropyl)benzenepropanamine, phenpropamine
Alverine is a drug used for functional gastrointestinal disorders. Alverine is a smooth muscle relaxant. Smooth muscle is a type of muscle that is not under voluntary control; it is the muscle present in places such as the gut and uterus.
Chemical data
- Formula
- C20H27N
- Molecular weight
- 281.4 g/mol
- IUPAC name
- N-ethyl-3-phenyl-N-(3-phenylpropyl)propan-1-amine
via PubChem
Drug data · ChEMBL
- Max clinical phase
- Phase 2
- Molecule type
- Small molecule
- Indications
- gastrointestinal disease, portal hypertension
via ChEMBL · EBI
Research
66 papers- Alverine citrate promotes myogenic differentiation and ameliorates muscle atrophy.Biochemical and biophysical research communications · 2022
- Anti-Inflammatory Functions of Alverine via Targeting Src in the NF-κB Pathway.Biomolecules · 2020
- Antispasmodics for Chronic Abdominal Pain: Analysis of North American Treatment Options.The American journal of gastroenterology · 2021
- Effect of alverine citrate plus simethicone in colonoscopy: a randomized controlled trial.Scientific reports · 2024
- Alverine citrate induced acute hepatitis.World journal of gastroenterology · 2004
via PubMed
Wikidata facts
- Mass
- 281.21435
- Has use
- medication
Show 5 more facts
- chemical formula
- C₂₀H₂₇N
- World Health Organisation international non-proprietary name
- alverine
- canonical SMILES
- CCN(CCCC1=CC=CC=C1)CCCC2=CC=CC=C2
- subject has role
- parasympatholytic
- different from
- alvameline
via Wikidata · CC0
~4 min read
Encyclopedic overview
5 sectionsContents
- Adverse effects
- Mechanism of action
- Total synthesis
- Development and marketing
- References
Alverine is a drug used for functional gastrointestinal disorders. Alverine is a smooth muscle relaxant. Smooth muscle is a type of muscle that is not under voluntary control; it is the muscle present in places such as the gut and uterus.
==Adverse effects==
Excerpted from Wikipedia’s “alverine” article, available under the CC BY-SA 4.0 licence.
Gallery (3)
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via Wikidata sitelinks · CC0