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dazopride

Structure via PubChem · Public domain (PubChem)

EntityQ5243687· pop 9· linked from 1,399 articles

Dazopride (AHR-5531) is an antiemetic and gastroprokinetic agent of the benzamide class which was never marketed. It acts as a 5-HT3 receptor antagonist and 5-HT4 receptor agonist. In addition to its gastrointestinal effects, dazopride facilitates learning and memory in mice.

Chemical data

Formula
C15H23ClN4O2
Molecular weight
326.82 g/mol
IUPAC name
4-amino-5-chloro-N-(1,2-diethylpyrazolidin-4-yl)-2-methoxybenzamide
SMILES
CCN1CC(CN1CC)NC(=O)C2=CC(=C(C=C2OC)N)Cl
InChIKey
YFXIKEZOBJFVAQ-UHFFFAOYSA-N
XLogP
2
Polar surface area
70.8 Ų
H-bond donors
2
H-bond acceptors
5
Formal charge
0

via PubChem

Drug data · ChEMBL

Max clinical phase
Phase 2
Molecule type
Small molecule

via ChEMBL · EBI

Wikidata facts

Mass
326.151
Show 3 more facts
canonical SMILES
CCN1CC(CN1CC)NC(=O)C2=CC(=C(C=C2OC)N)Cl
chemical formula
C₁₅H₂₃ClN₄O₂
Commons category
Dazopride
Sources (2)

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Encyclopedic overview

2 sections
Contents
  • See also
  • References

Dazopride (AHR-5531) is an antiemetic and gastroprokinetic agent of the benzamide class which was never marketed. It acts as a 5-HT3 receptor antagonist and 5-HT4 receptor agonist. In addition to its gastrointestinal effects, dazopride facilitates learning and memory in mice.

== See also == Antiemetic Benzamide

Excerpted from Wikipedia’s “dazopride” article, available under the CC BY-SA 4.0 licence.

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