Structure via PubChem · Public domain (PubChem)
ramosetron
Sign in to saveRamosetron (INN) is a serotonin 5-HT3 receptor antagonist for the treatment of nausea and vomiting. Ramosetron is also indicated for a treatment of "diarrhea-predominant irritable bowel syndrome in male and women". In India it is marketed under the brand name of Ibset.
Chemical data
- Formula
- C17H17N3O
- Molecular weight
- 279.34 g/mol
- IUPAC name
- (1-methylindol-3-yl)-[(5R)-4,5,6,7-tetrahydro-3H-benzimidazol-5-yl]methanone
via PubChem
Drug data · ChEMBL
- Max clinical phase
- Approved
- Molecule type
- Small molecule
- First approval
- 2015
- Indications
- post operative nausea and vomiting, Radiation-induced nausea and vomiting, gastric cancer, Vomiting
via ChEMBL · EBI
Research
400 papers- Effects of Ramosetron on Nausea and Vomiting Following Spinal Surgery: A Meta-Analysis.Current therapeutic research, clinical and experimental · 2022
- Drugs for preventing postoperative nausea and vomiting in adults after general anaesthesia: a network meta-analysis.The Cochrane database of systematic reviews · 2020
- Ramosetron for the treatment of irritable bowel syndrome with diarrhea: a systematic review and meta-analysis of randomized controlled trials.BMC gastroenterology · 2018
- Ramosetron, a 5-HT3 receptor antagonist for the control of nausea and vomiting.Drugs of today (Barcelona, Spain : 1998) · 2002
- Comparison of ramosetron and ondansetron for the prevention of postoperative nausea and vomiting in patients undergoing laparoscopic surgery: a meta-analysis of randomized controlled trials.The Journal of international medical research · 2019
via PubMed
Wikidata facts
- Mass
- 279.137162
Show 4 more facts
- chemical formula
- C₁₇H₁₇N₃O
- isomeric SMILES
- CN1C=C(C2=CC=CC=C21)C(=O)[C@@H]3CCC4=C(C3)NC=N4
- canonical SMILES
- CN1C=C(C2=CC=CC=C21)C(=O)C3CCC4=C(C3)NC=N4
- Commons category
- Ramosetron
Sources (2)
via Wikidata · CC0
~1 min read
Article
1 sectionsContents
- References
Ramosetron (INN) is a serotonin 5-HT3 receptor antagonist for the treatment of nausea and vomiting. Ramosetron is also indicated for a treatment of "diarrhea-predominant irritable bowel syndrome in male and women". In India it is marketed under the brand name of Ibset.
It is only licensed for use in Japan and selected Southeast Asian countries. In Japan it is sold under the trade name Irribow. and in India as Ibset . 'Elsewhere it is commonly sold under the trade name Nasea and in India as Nozia (150 μg/mL injection & 100 μg oral tablet).
Available in 10 languages
via Wikidata sitelinks · CC0