Structure via PubChem · Public domain (PubChem)
amitrole
Sign in to saveAlso known as Aminotriazole, 3-Aminotriazole, 2-Amino-1,3,4-triazole, 3-Amino-1,2,4-triazole, 1H-1,2,4-Triazol-3-amine, 3,A-T, 3-Amino-1H-1,2,4-triazole
thumb|3-Amino-1,2,4-triazole in powder form 3-Amino-1,2,4-triazole (3-AT) is a heterocyclic organic compound that consists of 1,2,4-triazole with an amino group as a substituent.
In the Vinony graph
Within Vinony's link graph, amitrole is referenced by 180 other articles, and connects out to phenoxy herbicide, food and arsenic.
It sits within the topics Chembox having GHS data, Chembox image size set and Cranberries.
Its subject is documented across 18 Wikipedia language editions.
Chemical data
- Formula
- C2H4N4
- Molecular weight
- 84.08 g/mol
- IUPAC name
- 1H-1,2,4-triazol-5-amine
- SMILES
- C1=NNC(=N1)N
- InChIKey
- KLSJWNVTNUYHDU-UHFFFAOYSA-N
- XLogP
- -0.4
- Polar surface area
- 67.6 Ų
- H-bond donors
- 2
- H-bond acceptors
- 3
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
- Molecule type
- Small molecule
via ChEMBL · EBI
Research
11,495 papers- Amitrole.Report on carcinogens : carcinogen profiles · 2004
- Amitrole.IARC monographs on the evaluation of the carcinogenic risk of chemicals to humans · 1986
- Establishment and Characterization of Amitrole-Induced Mouse Thyroid Adenomatous Nodule-Derived Cell Lines.Thyroid : official journal of the American Thyroid Association · 2024
- Amitrole.Report on carcinogens : carcinogen profiles · 2011
- Amitrole.Report on carcinogens : carcinogen profiles · 2002
via PubMed
Wikidata facts
- Subclass of
- heterocyclic compound
- Mass
- 84.044
- Has use
- herbicide
Show 11 more facts
- melting point
- 318
- chemical formula
- C₂H₄N₄
- density
- 1.14
- NIOSH Pocket Guide ID
- 0027
- vapor pressure
- 0.000008
- solubility
- 28
- time-weighted average exposure limit
- 0.2
- median lethal dose (LD50)
- 1100
- canonical SMILES
- C1=NNC(=N1)N
- subject has role
- carcinogen
- Commons category
- 3-Amino-1,2,4-triazole
Sources (4)
via Wikidata · CC0
~2 min read
Encyclopedic overview
3 sectionsContents
- Applications in microbiology
- 1959 cranberry contamination
- References
thumb|3-Amino-1,2,4-triazole in powder form 3-Amino-1,2,4-triazole (3-AT) is a heterocyclic organic compound that consists of 1,2,4-triazole with an amino group as a substituent.
3-AT is a competitive inhibitor of the product of the HIS3 gene, imidazoleglycerol-phosphate dehydratase. Imidazoleglycerol-phosphate dehydratase is an enzyme catalyzing the sixth step of histidine production.
Excerpted from Wikipedia’s “amitrole” article, available under the CC BY-SA 4.0 licence.