antidepressant

Also known as antidepressant drugs, antidepressants, thymoleptic, antidepressive agent, antidepressive agents

Antidepressants, also known in the past as psychic energizers, are a class of medications used to treat major depressive disorder, anxiety disorders, chronic pain, and addiction.

AI overview

Antidepressants are medications designed to treat major depressive disorder, anxiety disorders, chronic pain, and addiction. They matter because they provide a medical option for managing conditions that significantly affect people's quality of life and well-being.

AI-generated from the Wikipedia summary — may contain errors.

Key facts

Drug class.Image: Venlafaxine structure.svg
Drug class.ImageClass: skin-invert-image
Drug class.Width: 175px
Drug class.Caption: Venlafaxine (brand name Effexor), an antidepressant acting as a serotonin–norepinephrine reuptake inhibitor (SNRI).
Drug class.Synonyms: Psychic energizer; Mood elevator; Thymoleptic; Depression pill
Drug class.Use: Depressive disorders, anxiety disorders, chronic pain, and addiction
Drug class.ATC_prefix: N06A
Drug class.Mechanism_of_action: Varies
Drug class.Chemical_class: Varies
Drug class.MedlinePlus: antidepressants
Drug class.Consumer_Reports: antidepressants
Drug class.medicinenet: antidepressants
Drug class.rxlist: 100734
Drug class.MeshID: D000928

via Wikipedia infobox

Research

213,526 papers

Antidepressant-induced sexual dysfunction.ReviewThe Medical journal of Australia · 2020Rothmore JDOI: 10.5694/mja2.50522
Mechanism of action of antidepressant medications.ReviewThe Journal of clinical psychiatry · 1999Feighner JP
Antidepressant deprescribing: State of the art and recommendations-A literature overview.ReviewEuropean journal of clinical pharmacology · 2024Romagnoli A, Zovi A, Santoleri F et al.DOI: 10.1007/s00228-023-03617-x
Antidepressant-induced hepatotoxicity.ReviewExpert opinion on drug safety · 2003Lucena MI, Carvajal A, Andrade RJ et al.DOI: 10.1517/14740338.2.3.249
Antidepressant withdrawal phenomena.ReviewBiological psychiatry · 1984Dilsaver SC, Greden JF
Antidepressant discontinuation syndromes.ReviewDrug safety · 2001Haddad PMDOI: 10.2165/00002018-200124030-00003
Antidepressant Pharmacogenetics.The American journal of psychiatry · 2017Singh AB, Bousman CADOI: 10.1176/appi.ajp.2017.17020173
Antidepressant-Induced Hyponatremia in Older Adults.ReviewThe Consultant pharmacist : the journal of the American Society of Consultant Pharmacists · 2016Viramontes TS, Truong H, Linnebur SADOI: 10.4140/TCP.n.2016.139

via PubMed

Wikidata facts

Image: Sertraline-50mg-multilab.jpg

Show 5 more facts

Commons category: Antidepressants
name in kana: こううつやく
NCI Thesaurus ID: C265
WordLift URL: data.medicalrecords.com/medicalrecords/healthwise/antidepressants
name: thymoleptic

Sources (13)

via Wikidata · CC0

~73 min read

Article

60 sections

Contents

Medical uses
Major depressive disorder
Anxiety disorders
Generalized anxiety disorder
Social anxiety disorder
Obsessive–compulsive disorder
Post–traumatic stress disorder
Panic disorder
Eating disorders
Pain
Fibromyalgia
Neuropathic pain
Other uses
Limitations and strategies
Switching antidepressants
Augmentation and combination
Long-term use and stopping
Adverse effects
Pregnancy
Antidepressant-induced mania
Suicide
Sexual dysfunction
Emotional blunting
Changes in weight
Bone loss
Risk of death
Discontinuation syndrome
Pharmacology
Monoamine hypothesis
Other biological theories
Placebo mechanisms
Types
Selective serotonin reuptake inhibitors
Serotonin–norepinephrine reuptake inhibitors
Serotonin modulators and stimulators
Serotonin antagonists and reuptake inhibitors
Tricyclic antidepressants
Tetracyclic antidepressants
Monoamine oxidase inhibitors
NMDA receptor antagonists
Others
Adjuncts
Less common adjuncts
History
Isoniazid, iproniazid, and imipramine
Second-generation antidepressants
Rapid-acting antidepressants
Research
Publication bias and aged research
Society and culture
Prescription trends
United Kingdom
United States
Adherence
Social science perspective
Environmental impacts
See also
References
Further reading
External links

Antidepressants, also known in the past as psychic energizers, are a class of medications used to treat major depressive disorder, anxiety disorders, chronic pain, and addiction.

Common side effects of antidepressants include dry mouth, weight gain, dizziness, headaches, akathisia, sexual dysfunction, and emotional blunting. There is an increased risk of suicidal thinking and behavior when taken by children, adolescents, and young adults. Discontinuation syndrome, which resembles recurrent depression in the case of the SSRI class, may occur after stopping the intake of any antidepressant, having effects which may be permanent and irreversible. Tapering off medications gradually is shown to reduce the risk of withdrawal complications.