Structure via PubChem · Public domain (PubChem)
atomoxetine
Sign in to saveAlso known as LY-139603, Strattera®, (-)-Tomoxetine, Tomoxetine, Tomoxetina, Tomoxetinum
Atomoxetine, sold under the brand name Strattera, is a selective norepinephrine reuptake inhibitor (sNRI) medication used to treat attention deficit hyperactivity disorder (ADHD) and, to a lesser extent, cognitive disengagement syndrome (CDS). It may be used alone or along with psychostimulant medication. It enhances the executive functions of self-motivation, sustained attention, inhibition, working memory, reaction time, and emotional self-regulation. Use of atomoxetine is only recommended for those who are at least six years old. It is taken orally. The effectiveness of atomoxetine is compa
Key facts
- Drug.Verifiedfields
- changed
- Drug.Watchedfields
- changed
- Drug.verifiedrevid
- 458780865
- Drug.image
- Atomoxetine structure.svg
- Drug.image_class
- skin-invert-image
- Drug.width
- 220
- Drug.image2
- Atomoxetine ball-and-stick model.png
- Drug.image_class2
- bg-transparent
- Drug.width2
- 240
- Drug.tradename
- Strattera, others
- Drug.MedlinePlus
- a603013
- Drug.DailyMedID
- Atomoxetine
- Drug.pregnancy_AU
- B3
- Drug.routes_of_administration
- By mouth
- Drug.class
- Norepinephrine reuptake inhibitor
- Drug.ATC_prefix
- N06
- Drug.ATC_suffix
- BA09
- Drug.legal_AU
- S4
via Wikipedia infobox
Chemical data
- Formula
- C17H21NO
- Molecular weight
- 255.35 g/mol
- IUPAC name
- (3R)-N-methyl-3-(2-methylphenoxy)-3-phenylpropan-1-amine
- SMILES
- CC1=CC=CC=C1O[C@H](CCNC)C2=CC=CC=C2
- InChIKey
- VHGCDTVCOLNTBX-QGZVFWFLSA-N
- XLogP
- 3.7
- Polar surface area
- 21.3 Ų
- H-bond donors
- 1
- H-bond acceptors
- 2
- Formal charge
- 0
via PubChem
Wikidata facts
- Mass
- 255.162314
Show 6 more facts
- Commons category
- Atomoxetine
- chemical formula
- C₁₇H₂₁NO
- isomeric SMILES
- CC1=CC=CC=C1O[C@H](CCNC)C2=CC=CC=C2
- canonical SMILES
- CC1=CC=CC=C1OC(CCNC)C2=CC=CC=C2
- World Health Organisation international non-proprietary name
- atomoxetine
- defined daily dose
- 80
via Wikidata · CC0
~19 min read
Article
22 sectionsContents
- Medical uses
- Attention deficit hyperactivity disorder
- Other uses
- Cognitive disengagement syndrome
- Traumatic brain injury
- Contraindications
- Side effects
- Overdose
- Interactions
- Pharmacology
- Pharmacodynamics
- Pharmacokinetics
- Pharmacogenomics
- Chemistry
- Synthesis
- Detection in biological fluids
- History
- Society and culture
- Brand names
- Research
- References
- Further reading
Atomoxetine, sold under the brand name Strattera, is a selective norepinephrine reuptake inhibitor (sNRI) medication used to treat attention deficit hyperactivity disorder (ADHD) and, to a lesser extent, cognitive disengagement syndrome (CDS). It may be used alone or along with psychostimulant medication. It enhances the executive functions of self-motivation, sustained attention, inhibition, working memory, reaction time, and emotional self-regulation. Use of atomoxetine is only recommended for those who are at least six years old. It is taken orally. The effectiveness of atomoxetine is comparable to the commonly prescribed stimulant medication methylphenidate.
Common side effects of atomoxetine include abdominal pain, decreased appetite, nausea, feeling tired, and dizziness. Serious side effects may include angioedema, liver problems, stroke, psychosis, heart problems, suicide, and aggression. There is a lack of data regarding its safety during pregnancy; as of 2019, its safety during pregnancy and for use during breastfeeding is not certain.