Apelin
Sign in to saveAlso known as APJ endogenous ligand, AGTRL1 ligand, APLN
Apelin (also known as APLN) is a peptide that in humans is encoded by the APLN gene. Apelin is one of two endogenous ligands for the G-protein-coupled APJ receptor that is expressed at the surface of some cell types. It is widely expressed in various organs such as the heart, lung, kidney, liver, adipose tissue, gastrointestinal tract, brain, adrenal glands, endothelium, and human plasma.
~8 min read
Article
14 sectionsContents
- Discovery
- Biosynthesis
- Physiological functions
- Vascular
- Cardiac
- Exercise
- Brain
- Adipose tissue
- Digestive
- Bone
- Muscle aging
- References
- Further reading
- External links
Apelin (also known as APLN) is a peptide that in humans is encoded by the APLN gene. Apelin is one of two endogenous ligands for the G-protein-coupled APJ receptor that is expressed at the surface of some cell types. It is widely expressed in various organs such as the heart, lung, kidney, liver, adipose tissue, gastrointestinal tract, brain, adrenal glands, endothelium, and human plasma.
== Discovery ==