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endothelium

File:Microscopic_anatomy_of_an_artery_en.svg · Wikimedia Commons · See Wikimedia Commons

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endothelium

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The endothelium (: endothelia) is a single layer of squamous endothelial cells that line the interior surface of blood vessels and lymphatic vessels. The endothelium forms an interface between circulating blood or lymph in the lumen and the rest of the vessel wall.

Key facts

Cell.Name
Endothelium
Cell.Image
Microscopic anatomy of an artery en.svg
Cell.Caption
Diagram showing the location of endothelial cells
Cell.Image2
Microvessel.jpg
Cell.Caption2
Transmission electron micrograph of a microvessel showing endothelial cells, which encircle an erythrocyte (E), forming the innermost layer of the vessel, the tunica intima.
Cell.System
Circulatory system
Cell.Location
Lining of the inner surface of blood vessels and lymphatic vessels

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Research

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Commons category
Endothelium
NCI Thesaurus ID
C12481
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~10 min read

Article

14 sections
Contents
  • Structure
  • Terminology
  • Function
  • Blood vessel formation
  • Host immune response
  • Clinical significance
  • Research
  • Cancer
  • Diet
  • Covid-19
  • History
  • See also
  • References
  • External links

The endothelium (: endothelia) is a single layer of squamous endothelial cells that line the interior surface of blood vessels and lymphatic vessels. The endothelium forms an interface between circulating blood or lymph in the lumen and the rest of the vessel wall.

Endothelial cells in direct contact with blood are called vascular endothelial cells whereas those in direct contact with lymph are known as lymphatic endothelial cells. Vascular endothelial cells line the entire circulatory system, from the heart to the smallest capillaries.

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