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bone marrow

Also known as marrow

cells and soft materials in the hollow space of long bones

AI overview

Bone marrow is the soft tissue found inside the hollow spaces of long bones in your body. It matters because it produces blood cells and immune cells that your body needs to function.

AI-generated from the Wikipedia summary — may contain errors.

Research

349,246 papers

BONE MARROW LESIONS: TWO PILLARS CONCEPT.ReviewActa clinica Croatica · 2023Ivković A, Vuletić F, Petrović T et al.DOI: 10.20471/acc.2023.62.s3.14
How I investigate bone marrow necrosis.ReviewInternational journal of laboratory hematology · 2019Deucher A, Wool GDDOI: 10.1111/ijlh.13091
Imaging paediatric bone marrow in immunocompromised patients.ReviewPediatric radiology · 2025Sirvent Cerdá SI, Muñiz IS, Esparza EGDOI: 10.1007/s00247-024-06153-7
The Spinal Bone Marrow in Health and Disease.ReviewMagnetic resonance imaging clinics of North America · 2025Gibbs WNDOI: 10.1016/j.mric.2025.02.002
Bone marrow and bone: a functional unit.ReviewThe Journal of endocrinology · 2002Compston JEDOI: 10.1677/joe.0.1730387
Role of Bone Marrow Aspirate in Orthopedic Trauma.ReviewThe Orthopedic clinics of North America · 2017Schottel PC, Warner SJDOI: 10.1016/j.ocl.2017.03.005
Highlights: Focus on Bone Marrow Pathology.ReviewJournal of clinical and experimental hematopathology : JCEH · 2018Ito MDOI: 10.3960/jslrt.58001
Bone and bone marrow: the same organ.ReviewArchives of biochemistry and biophysics · 2010Del Fattore A, Capannolo M, Rucci NDOI: 10.1016/j.abb.2010.07.020

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Wikidata facts

Image: 201405 marrow.png

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Commons category: Bone marrow
NCI Thesaurus ID: C12431

Sources (6)

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Article

Bone marrow is a semi-solid tissue found within the spongy (also known as cancellous) portions of bones. In birds and mammals, bone marrow is the primary site of new blood cell production (or haematopoiesis). It is composed of hematopoietic cells, marrow adipose tissue, and supportive stromal cells. In adult humans, bone marrow is primarily located in the ribs, vertebrae, sternum, and bones of the pelvis. Bone marrow comprises approximately 5% of total body mass in healthy adult humans, such that a person weighing 73 kg (161 lbs) will have around 3.7 kg (8 lbs) of bone marrow.

Human marrow produces approximately 500 billion blood cells per day, which join the systemic circulation via permeable vasculature sinusoids within the medullary cavity. All types of hematopoietic cells, including both myeloid and lymphoid lineages, are created in bone marrow; however, lymphoid cells must migrate to other lymphoid organs (e.g. thymus) in order to complete maturation.