APOC1

Name

apolipoprotein C1

Type

protein-coding

Position

44,913,133–44,920,054 (+)

Aliases

APOC1B, Apo-CI, ApoC-I, apo-CIB, apoC-IB

Ensembl

ENSG00000130208

RefSeq RNA

NM_001321065.2, NM_001321066.2, NM_001379687.1, NM_001645.5

RefSeq protein

NP_001307994.1, NP_001307995.1, NP_001366616.1, NP_001636.1

This gene encodes a member of the apolipoprotein C1 family. This gene is expressed primarily in the liver, and it is activated when monocytes differentiate into macrophages. The encoded protein plays a central role in high density lipoprotein (HDL) and very low density lipoprotein (VLDL) metabolism. This protein has also been shown to inhibit cholesteryl ester transfer protein in plasma. A pseudogene of this gene is located 4 kb downstream in the same orientation, on the same chromosome. This gene is mapped to chromosome 19, where it resides within a apolipoprotein gene cluster. Alternative splicing and the use of alternative promoters results in multiple transcript variants. [provided by RefSeq, Sep 2016].

via MyGene.info

Gene · Ensembl

apolipoprotein C1

Symbol

APOC1

Biotype

Protein coding

Organism

Homo sapiens

Location

19:44,913,133-44,920,054

Strand

Forward (+)

Assembly

GRCh38

Wikidata facts

Instance of

gene

Image

Protein APOC1 PDB 1ioj.png

via Wikidata · CC0