baicalin

Also known as Baicalein 7-O-glucuronide, 7-D-glucuronic acid-5,6-dihydroxyflavone, 5,6-dihydroxy-4-oxo-2-phenyl-4H-1-benzopyran-7-yl beta-D-glucopyranosiduronic acid, 5,6,7-trihydroxyflavone 7-O-beta-D-glucuronide

Baicalin is the glucuronide of the polyphenolic compound baicalein.

Research

3,369 papers

The Pharmacological Efficacy of Baicalin in Inflammatory Diseases.International journal of molecular sciences · 2023
Baicalin prevents LPS-induced activation of TLR4/NF-κB p65 pathway and inflammation in mice via inhibiting the expression of CD14.Acta pharmacologica Sinica · 2021
Baicalin induces ferroptosis in osteosarcomas through a novel Nrf2/xCT/GPX4 regulatory axis.Phytomedicine : international journal of phytotherapy and phytopharmacology · 2023
Baicalin and baicalein in modulating tumor microenvironment for cancer treatment: A comprehensive review with future perspectives.Pharmacological research · 2024
Baicalin inhibits PANoptosis by blocking mitochondrial Z-DNA formation and ZBP1-PANoptosome assembly in macrophages.Acta pharmacologica Sinica · 2025

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Wikidata facts

Mass: 446.085

Show 3 more facts

chemical formula: C₂₁H₁₈O₁₁
canonical SMILES: C1=CC=C(C=C1)C2=CC(=O)C3=C(C(=C(C=C3O2)OC4C(C(C(C(O4)C(=O)O)O)O)O)O)O
isomeric SMILES: C1=CC=C(C=C1)C2=CC(=O)C3=C(C(=C(C=C3O2)O[C@H]4[C@@H]([C@H]([C@@H]([C@H](O4)C(=O)O)O)O)O)O)O

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Article

3 sections

Contents

Natural occurrences
Medical uses
References

Baicalin is the glucuronide of the polyphenolic compound baicalein.

== Natural occurrences == Baicalin is found in several species in the genus Scutellaria, including Scutellaria baicalensis, and Scutellaria lateriflora. There are 10 mg/g baicalin in Scutellaria galericulata leaves. It is also present in the bark isolate of the Oroxylum indicum tree.