BAPTA
Sign in to saveAlso known as Bapeta, 1,2-Bis(o-aminophenoxy)ethane-N,N,N',N'-tetraacetic acid, 1,2-Bis(2-aminophenoxy)ethane-N,N,N',N'-tetraacetic acid
BAPTA (1,2-bis(o-aminophenoxy)ethane-N,N,N′,N′-tetraacetic acid) is an aminopolycarboxylic acid with a high affinity for calcium. It is a white solid. It is used in research to chelate Ca2+, as it behaves similarly to EGTA and EDTA.
Research
6,536 papers- Cellular effects of BAPTA: Are they only about Ca(2+) chelation?Biochimica et biophysica acta. Molecular cell research · 2024
- Intracellular BAPTA directly inhibits PFKFB3, thereby impeding mTORC1-driven Mcl-1 translation and killing MCL-1-addicted cancer cells.Cell death & disease · 2023
- Calcium chelation independent effects of BAPTA on endogenous ANO6 channels in HEK293T cells.Biochemical and biophysical research communications · 2024
- Calcium imaging and BAPTA loading of amygdala astrocytes in mouse brain slices.STAR protocols · 2022
- BAPTA, a calcium chelator, neuroprotects injured neurons in vitro and promotes motor recovery after spinal cord transection in vivo.CNS neuroscience & therapeutics · 2021
via PubMed
Wikidata facts
- Mass
- 476.143
Show 3 more facts
- chemical formula
- C₂₂H₂₄N₂O₁₀
- canonical SMILES
- C1=CC=C(C(=C1)N(CC(=O)O)CC(=O)O)OCCOC2=CC=CC=C2N(CC(=O)O)CC(=O)O
- Commons category
- BAPTA
via Wikidata · CC0
~1 min read
Article
3 sectionsContents
- Complexation
- See also
- References
BAPTA (1,2-bis(o-aminophenoxy)ethane-N,N,N′,N′-tetraacetic acid) is an aminopolycarboxylic acid with a high affinity for calcium. It is a white solid. It is used in research to chelate Ca2+, as it behaves similarly to EGTA and EDTA.
==Complexation== BAPTA, as its conjugate base, binds calcium ions as a decadentate ligand:
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