Structure via PubChem · Public domain (PubChem)
dimercaprol
Sign in to saveAlso known as British Anti-Lewisite, 2,3-Dimercaptol-1-propanol, 2,3-Mercaptopropanol, Dithioglycerol, Dithioglycerine, 3-Hydroxy-1,2-propanedithiol, British antilewisite, Dimercaprolum
Dimercaprol, also called British anti-Lewisite (BAL), is a medication used to treat acute poisoning by arsenic, mercury, gold, and lead. It may also be used for antimony, thallium, or bismuth poisoning, although the evidence for those uses is not very strong. It is given by injection into a muscle.
Key facts
- Drug.IUPAC_name
- 2,3-Bis(sulfanyl)propan-1-ol
- Drug.image
- Dimercaprol.svg
- Drug.image_class
- skin-invert-image
- Drug.image2
- Dimercaprol-3D-balls.png
- Drug.image_class2
- bg-transparent
- Drug.caption
- Skeletal formula and ball and stick model of dimercaprol
- Drug.tradename
- BAL in Oil
- Drug.DailyMedID
- Dimercaprol
- Drug.pregnancy_US
- C
- Drug.routes_of_administration
- intramuscular
- Drug.legal_US
- Rx-only
- Drug.excretion
- Urine
- Drug.CAS_number
- 59-52-9
- Drug.ATC_prefix
- V03
- Drug.ATC_suffix
- AB09
- Drug.PubChem
- 3080
- Drug.DrugBank
- DB06782
- Drug.ChemSpiderID
- 2971
via Wikipedia infobox
Chemical data
- Formula
- C3H8OS2
- Molecular weight
- 124.23 g/mol
- IUPAC name
- 2,3-bis(sulfanyl)propan-1-ol
- SMILES
- C(C(CS)S)O
- InChIKey
- WQABCVAJNWAXTE-UHFFFAOYSA-N
- XLogP
- 0.2
- Polar surface area
- 22.2 Ų
- H-bond donors
- 3
- H-bond acceptors
- 3
- Formal charge
- 0
via PubChem
Research
2,367 papers- DIMERCAPROL: BAL.Bulletin. American Society of Hospital Pharmacists · 1946
- DIMERCAPROL for hepatolenticular degeneration.Lancet (London, England) · 1952
- Are we ready to replace dimercaprol (BAL) as an arsenic antidote?Human & experimental toxicology · 1997
- Dimercaprol is an acrolein scavenger that mitigates acrolein-mediated PC-12 cells toxicity and reduces acrolein in rat following spinal cord injury.Journal of neurochemistry · 2017
- British anti-Lewisite (dimercaprol): an amazing history.Annals of emergency medicine · 2003
via PubMed
Wikidata facts
- Mass
- 124.002
Show 4 more facts
- chemical formula
- C₃H₈OS₂
- canonical SMILES
- C(C(CS)S)O
- World Health Organisation international non-proprietary name
- dimercaprol
- Commons category
- Dimercaprol
via Wikidata · CC0
~4 min read
Article
6 sectionsContents
- Medical uses
- Mechanism of action
- History
- See also
- References
- External links
Dimercaprol, also called British anti-Lewisite (BAL), is a medication used to treat acute poisoning by arsenic, mercury, gold, and lead. It may also be used for antimony, thallium, or bismuth poisoning, although the evidence for those uses is not very strong. It is given by injection into a muscle.
Common side effects include high blood pressure, pain at the site of the injection, vomiting, and fever. It is not recommended for people with peanut allergies as it is typically formulated as a suspension in peanut oil. It is unclear if use in pregnancy is safe for the baby. Dimercaprol is a chelator and works by binding with heavy metals. It has a very pungent odor.