biotin

Also known as D-(+)-biotin, vitamin B7, (3aS,4S,6aR)-Hexahydro-2-oxo-1H-thieno[3,4-d]imidazole-4-valeric acid, 5-(2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentanoic acid, cis-Hexahydro-2-oxo-1H-thieno(3,4)imidazole-4-valeric acid, (+)-cis-Hexahydro-2-oxo-1H-thieno[3,4]imidazole-4-valeric acid, cis-Tetrahydro-2-oxothieno(3,4-d)imidazoline-4-valeric acid, cis-(+)-Tetrahydro-2-oxothieno[3,4]imidazoline-4-valeric acid

alt=3D space-filling model of Biotin rotating about an axis (GIF)|thumb|3D space-filling model of biotin rotating about an axis Biotin (also known as vitamin B7 and Vitamin H) is one of the B vitamins – a group of essential dietary micronutrients. Present in every living cell, it is involved as a cofactor for enzymes in numerous metabolic processes, both in humans and in other organisms, primarily related to the biochemistry of fats, carbohydrates, and amino acids.

AI overview

Biotin, also known as vitamin B7, is an essential nutrient found in every living cell that helps enzymes carry out important metabolic processes in your body. It plays a key role in how your body breaks down and uses fats, carbohydrates, and amino acids for energy and other vital functions.

AI-generated from the Wikipedia summary — may contain errors.

Chemical data

Formula: C10H16N2O3S
Molecular weight: 244.31 g/mol
IUPAC name: 5-[(3aS,4S,6aR)-2-oxo-1,3,3a,4,6,6a-hexahydrothieno[3,4-d]imidazol-4-yl]pentanoic acid
SMILES: C1[C@H]2[C@@H]([C@@H](S1)CCCCC(=O)O)NC(=O)N2
InChIKey: YBJHBAHKTGYVGT-ZKWXMUAHSA-N
XLogP: 0.3
Polar surface area: 104 Å²
H-bond donors: 3
H-bond acceptors: 4
Formal charge: 0

via PubChem

Research

38,464 papers

Biotin: From Nutrition to Therapeutics.ReviewThe Journal of nutrition · 2017Mock DMDOI: 10.3945/jn.116.238956
Biotin for the treatment of nail disease: what is the evidence?ReviewThe Journal of dermatological treatment · 2018Lipner SR, Scher RKDOI: 10.1080/09546634.2017.1395799
Biotin.ReviewVitamins and hormones · 1989Dakshinamurti K, Chauhan JDOI: 10.1016/s0083-6729(08)60398-2
Biotin: DNA to diet.ReviewThe Journal of nutritional biochemistry · 2025Karalia S, Meena VKDOI: 10.1016/j.jnutbio.2025.110081
Immunoassay design and biotin interference.ReviewAdvances in clinical chemistry · 2022Dasgupta ADOI: 10.1016/bs.acc.2022.03.005
Biotin.ReviewWorld review of nutrition and dietetics · 1986Hommes FADOI: 10.1159/000413026
Biotin induced biochemical hyperthyroidism: a case report and review of the literature.ReviewJournal of medical case reports · 2023James A, Stalan J, Kuzhively JDOI: 10.1186/s13256-023-04002-z
Molecular Mechanisms of Biotin in Modulating Inflammatory Diseases.ReviewNutrients · 2024Sakurai-Yageta M, Suzuki YDOI: 10.3390/nu16152444

via PubMed

Wikidata facts

Mass: 244.088163372

Show 5 more facts

Commons category: Biotin
chemical formula: C₁₀H₁₆N₂O₃S
isomeric SMILES: C1[C@H]2[C@@H]([C@@H](S1)CCCCC(=O)O)NC(=O)N2
canonical SMILES: C1C2C(C(S1)CCCCC(=O)O)NC(=O)N2
melting point: 230.0

Sources (8)

via Wikidata · CC0

~21 min read

Article

24 sections

Contents

Chemical description
Dietary recommendations
Safety
Labeling regulations
Food sources
Physiology
Absorption
Metabolism and excretion
Factors that affect biotin requirements
Biosynthesis
Cofactor biochemistry
Deficiency
Diagnosis
Deficiency as a result of metabolic disorders
Use in biotechnology
Interference with medical laboratory results
History
Research
Multiple sclerosis
Hair, nails, skin
Animals
See also
References
External links

When isolated, biotin is a white, needle-like crystalline solid. Biotin is obtained from foods, particularly meats and liver, and is sold as a dietary supplement.