Structure via PubChem · Public domain (PubChem)
bromadiolone
Sign in to savethumb|right|Warning label on a tube of rat poison containing bromadiolone on a Levee|dike of the [[Scheldt river in Steendorp, Belgium]] Bromadiolone is a potent anticoagulant rodenticide. It is a second-generation 4-hydroxycoumarin derivative and vitamin K antagonist, often called a "super-warfarin" for its added potency and tendency to accumulate in the liver of the poisoned organism. When first introduced to the UK market in 1980, it was effective against rodent populations that had become resistant to first generation anticoagulants.
Chemical data
- Formula
- C30H23BrO4
- Molecular weight
- 527.4 g/mol
- IUPAC name
- 3-[3-[4-(4-bromophenyl)phenyl]-3-hydroxy-1-phenylpropyl]-4-hydroxychromen-2-one
- SMILES
- C1=CC=C(C=C1)C(CC(C2=CC=C(C=C2)C3=CC=C(C=C3)Br)O)C4=C(C5=CC=CC=C5OC4=O)O
- InChIKey
- OWNRRUFOJXFKCU-UHFFFAOYSA-N
- XLogP
- 6.1
- Polar surface area
- 66.8 Ų
- H-bond donors
- 2
- H-bond acceptors
- 4
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
- Molecule type
- Small molecule
via ChEMBL · EBI
Research
297 papers- A mini review on study of forensically important poisoning cases involving bromadiolone.Forensic science, medicine, and pathology · 2025
- A case of bromadiolone (superwarfarin) ingestion.CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne · 1992
- Acute bromadiolone intoxication.Journal of analytical toxicology · 2006
- [Study on the pharmacokinetics of bromadiolone in oral poisoning rabbits].Zhonghua lao dong wei sheng zhi ye bing za zhi = Zhonghua laodong weisheng zhiyebing zazhi = Chinese journal of industrial hygiene and occupational diseases · 2020
- Acute toxic encephalopathy following bromadiolone intoxication: a case report.BMC neurology · 2021
via PubMed
Wikidata facts
- Subclass of
- chemical compound
- Mass
- 526.078
- Image
- Rattenvergifwaarschuwing edit.JPG
- Has use
- rodenticide
Show 5 more facts
- chemical formula
- C₃₀H₂₃BrO₄
- canonical SMILES
- C1=CC=C(C=C1)C(CC(C2=CC=C(C=C2)C3=CC=C(C=C3)Br)O)C4=C(C5=CC=CC=C5OC4=O)O
- subject has role
- anticoagulant
- Commons category
- Bromadiolone
- described at URL
- deckaura.com/pages/tarot-card-database
Sources (2)
via Wikidata · CC0
~2 min read
Encyclopedic overview
5 sectionsContents
- Toxicity
- Chemistry
- Antidote
- See also
- References
thumb|right|Warning label on a tube of rat poison containing bromadiolone on a Levee|dike of the [[Scheldt river in Steendorp, Belgium]] Bromadiolone is a potent anticoagulant rodenticide. It is a second-generation 4-hydroxycoumarin derivative and vitamin K antagonist, often called a "super-warfarin" for its added potency and tendency to accumulate in the liver of the poisoned organism. When first introduced to the UK market in 1980, it was effective against rodent populations that had become resistant to first generation anticoagulants.
The product may be used both indoors and outdoors for rats and mice.
Excerpted from Wikipedia’s “bromadiolone” article, available under the CC BY-SA 4.0 licence.