difethialone
Sign in to saveDifethialone is an vitamin K antagonist anticoagulant used as a rodenticide. It is considered a second generation agent.
Wikidata facts
- Mass
- 538.060213
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- chemical formula
- C₃₁H₂₃BrO₂S
- canonical SMILES
- Oc1c(C2CC(Cc3ccccc23)c2ccc(cc2)-c2ccc(Br)cc2)c(=O)sc2ccccc12
- Commons category
- Difethialone
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Difethialone is an vitamin K antagonist anticoagulant used as a rodenticide. It is considered a second generation agent.
It belongs to the 4-thiochromenone or benzothiopyranone class of rodenticides, which differs from 4-hydroxycoumarins by the substitution of an oxygen atom with sulfur. It is especially similar to brodifacoum. It shares the same mechanism of inhibiting Vkorc1. It is effective for warfarin-resistant and warfarin-susceptible rodents. Its high potency makes resistance harder to evolve, though a few populations of rodents have nevertheless managed to do so.
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