Structure via PubChem · Public domain (PubChem)
bromethalin
Sign in to saveBromethalin is a neurotoxic rodenticide that damages the central nervous system.
Chemical data
- Formula
- C14H7Br3F3N3O4
- Molecular weight
- 577.93 g/mol
- IUPAC name
- N-methyl-2,4-dinitro-N-(2,4,6-tribromophenyl)-6-(trifluoromethyl)aniline
- SMILES
- CN(C1=C(C=C(C=C1[N+](=O)[O-])[N+](=O)[O-])C(F)(F)F)C2=C(C=C(C=C2Br)Br)Br
- InChIKey
- USMZPYXTVKAYST-UHFFFAOYSA-N
- XLogP
- 6.2
- Polar surface area
- 94.9 Ų
- H-bond donors
- 0
- H-bond acceptors
- 8
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
- Molecule type
- Small molecule
via ChEMBL · EBI
Wikidata facts
- Subclass of
- chemical compound
- Mass
- 574.793876664
Show 3 more facts
- chemical formula
- C₁₄H₇Br₃F₃N₃O₄
- canonical SMILES
- CN(C1=C(C=C(C=C1C(F)(F)F)[N+](=O)[O-])[N+](=O)[O-])C2=C(C=C(C=C2Br)Br)Br
- Commons category
- Bromethalin
Sources (2)
via Wikidata · CC0
~3 min read
Encyclopedic overview
4 sectionsContents
- History
- Mechanism of action
- Risk of poisoning to humans and pets
- References
Bromethalin is a neurotoxic rodenticide that damages the central nervous system.
==History== Bromethalin was discovered in the early 1980s through an approach to find replacement rodenticides for first-generation anticoagulants, especially to be useful against rodents that had become resistant to warfarin-type anticoagulant poisons. A structured study was undertaken to develop a substance that would be both poisonous to rodents, but also would be readily eaten by rodents. Bromethalin—N-methyl-2,4-dinitro-N (2,4,6-tribromophenyl)-6-(trifluoromethyl) benzeneamine— was the outcome of that study, as the specific formulation had both desired rodenticidal properties.
Excerpted from Wikipedia’s “bromethalin” article, available under the CC BY-SA 4.0 licence.