Structure via PubChem · Public domain (PubChem)
bunaftine
Sign in to saveBunaftine (or bunaphtine) is an antiarrhythmic agent. It is classified in class III.
Chemical data
- Formula
- C21H30N2O
- Molecular weight
- 326.5 g/mol
- IUPAC name
- N-butyl-N-[2-(diethylamino)ethyl]naphthalene-1-carboxamide
- SMILES
- CCCCN(CCN(CC)CC)C(=O)C1=CC=CC2=CC=CC=C21
- InChIKey
- WWGZXRYELYWJBD-UHFFFAOYSA-N
- XLogP
- 4.7
- Polar surface area
- 23.6 Ų
- H-bond donors
- 0
- H-bond acceptors
- 2
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
- Max clinical phase
- Phase 2
- Molecule type
- Small molecule
- Indications
- cardiac arrhythmia
via ChEMBL · EBI
Research
42 papers- [Electrophysiological effects of bunaftine, an antiarrhythmic drug, on action potential characteristics in ventricular muscle preparations].Nihon yakurigaku zasshi. Folia pharmacologica Japonica · 1986
- Effects of bunaftine on morphology, microfilament integrity, and mitotic activity in cultured human fibroblasts and HeLa cells.Cell and tissue research · 1984
- [Bunaftine in the treatment of arrhythmias].Cardiologia pratica · 1975
- Metabolic effects of bunaftine, a new antiarrhythmic agent: comparison with quinidine, ajmaline, procainamide, xylocaine and propranolol.Arzneimittel-Forschung · 1976
- Intropic effects of several antiarrhythmic drugs.Japanese heart journal · 1983
via PubMed
Wikidata facts
- Subclass of
- chemical compound
- Mass
- 326.236
Show 3 more facts
- chemical formula
- C₂₁H₃₀N₂O
- canonical SMILES
- CCCCN(CCN(CC)CC)C(=O)C1=CC=CC2=CC=CC=C21
- subject has role
- antiarrhythmic agent
Sources (2)
via Wikidata · CC0
~1 min read
Encyclopedic overview
1 sectionsContents
- References
Bunaftine (or bunaphtine) is an antiarrhythmic agent. It is classified in class III.
==References==
Excerpted from Wikipedia’s “bunaftine” article, available under the CC BY-SA 4.0 licence.