camostat
Sign in to saveAlso known as ONO-3403, FOY-305, FOY 305
Camostat is a serine protease inhibitor. Serine protease enzymes have a variety of functions in the body, and so camostat has a diverse range of uses. Camostat is approved in Japan for the treatment of chronic pancreatitis and postoperative reflux esophagitis. The oral proteolytic enzyme inhibitor has been on the market since 1985 under the trade name Foipan Tablets. The manufacturer is Ono Pharmaceutical. The drug is used in the treatment of some forms of cancer and is also effective against some viral infections, as well as inhibiting fibrosis in liver or kidney disease or pancreatitis.
Key facts
- Drug.PubChem
- 2536
- Drug.verifiedrevid
- 443459490
- Drug.IUPAC_name
- N,N-Dimethylcarbamoylmethyl 4-(4-guanidinobenzoyloxy)phenylacetate
- Drug.image
- Camostat.svg
- Drug.image_class
- skin-invert-image
- Drug.tradename
- Foipan
- Drug.synonyms
- FOY-305
- Drug.legal_US
- Not FDA approved
- Drug.legal_status
- Rx-only
- Drug.routes_of_administration
- Oral
- Drug.IUPHAR_ligand
- 6432
- Drug.CAS_number
- 59721-28-7
- Drug.ATC_prefix
- B02
- Drug.ATC_suffix
- AB04
- Drug.ChemSpiderID
- 2440
- Drug.ChEBI
- 135632
- Drug.UNII
- 0FD207WKDU
- Drug.KEGG
- D07606
via Wikipedia infobox
Research
571 papersvia PubMed
Wikidata facts
- Subclass of
- chemical compound
- Mass
- 398.159
- Has use
- medication
Show 4 more facts
- chemical formula
- C₂₀H₂₂N₄O₅
- canonical SMILES
- CN(C)C(=O)COC(=O)CC1=CC=C(C=C1)OC(=O)C2=CC=C(C=C2)N=C(N)N
- subject has role
- Trypsin inhibitor
- Commons category
- Camostat
via Wikidata · CC0
~3 min read
Encyclopedic overview
5 sectionsContents
- Pharmacology
- Side effects
- COVID-19
- References
- External links
Camostat is a serine protease inhibitor. Serine protease enzymes have a variety of functions in the body, and so camostat has a diverse range of uses. Camostat is approved in Japan for the treatment of chronic pancreatitis and postoperative reflux esophagitis. The oral proteolytic enzyme inhibitor has been on the market since 1985 under the trade name Foipan Tablets. The manufacturer is Ono Pharmaceutical. The drug is used in the treatment of some forms of cancer and is also effective against some viral infections, as well as inhibiting fibrosis in liver or kidney disease or pancreatitis.
== Pharmacology ==
Excerpted from Wikipedia’s “camostat” article, available under the CC BY-SA 4.0 licence.