ethamsylate
Sign in to saveAlso known as etamsylate, Dicynone
Etamsylate (sometimes spelled ethamsylate) is an antihemorrhagic agent which is believed to work by increasing resistance in the endothelium of capillaries and promoting platelet adhesion. It also inhibits biosynthesis and action of those prostaglandins which cause platelet disaggregation, vasodilation and increased capillary permeability.
Key facts
- Drug.N
- 1
- Drug.O
- 5
- Drug.S
- 1
- Drug.UNII
- 24YL531VOH
- Drug.CAS_number
- 2624-44-4
- Drug.PubChem
- 17506
- Drug.ChemSpiderID
- 16553
- Drug.Verifiedfields
- changed
- Drug.Watchedfields
- changed
- Drug.verifiedrevid
- 443973799
- Drug.image
- Ethamsylate.png
- Drug.image_class
- skin-invert-image
- Drug.image2
- Etamsylate ball-and-stick animation.gif
- Drug.tradename
- Cyclonamine, Dicynene, Dicynone, Haemostop, Menostat
- Drug.ATC_prefix
- B02
- Drug.ATC_suffix
- BX01
- Drug.KEGG
- D01282
- Drug.synonyms
- Diethylammonium 2,5-dihydroxybenzenesulfonate; diethylammonium dobesilate
via Wikipedia infobox
Research
238 papers- Ethamsylate for the prevention of morbidity and mortality in preterm or very low birth weight infants.The Cochrane database of systematic reviews · 2010
- Intrapartum ethamsylate.Lancet (London, England) · 1984
- Therapeutic efficacy and mechanism of action of ethamsylate, a long-standing hemostatic agent.American journal of therapeutics · 2006
- Interventions to Reduce Severe Brain Injury Risk in Preterm Neonates: A Systematic Review and Meta-analysis.JAMA network open · 2023
- Ethamsylate Attenuates Mutilated Secondary Pathogenesis and Exhibits a Neuroprotective Role in Experimental Model of Spinal Cord Injury.Neuroscience · 2022
via PubMed
Wikidata facts
- Mass
- 263.083
Show 3 more facts
- chemical formula
- C₁₀H₁₇NO₅S
- canonical SMILES
- CCNCC.C1=CC(=C(C=C1O)S(=O)(=O)O)O
- Commons category
- Etamsylate
Sources (2)
via Wikidata · CC0
~4 min read
Article
4 sectionsContents
- Indications
- Mechanism of action
- Veterinary use
- References
Etamsylate (sometimes spelled ethamsylate) is an antihemorrhagic agent which is believed to work by increasing resistance in the endothelium of capillaries and promoting platelet adhesion. It also inhibits biosynthesis and action of those prostaglandins which cause platelet disaggregation, vasodilation and increased capillary permeability.
Etamsylate is the salt of dobesilic acid and diethylamine.
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via Wikidata sitelinks · CC0