menadiol
Sign in to saveAlso known as 2-Methylnaphthalene-1,4-diol, Vitamin K3H2, Reduced vitamin K3, Reduced menadione, Methylnaphthohydroquinone, Dihydrovitamin K3, 2-Methylhydronaphthoquinone, 2-Methyl-1,4-naphthoquinol
Menadiol is an organic compound with the formula C6H4(COH)2(CH)(CH3). It is formally the p-hydroquinone derivative of 2-methylnaphthalene. The name vitamin K4 can refer to: specifically this compound, its various esters, e.g. menadiol diacetate (acetomenaphthone), menadiol dibutyrate, menadiol dimalonate, or its various salts, like menadiol sodium diphosphate (Kappadione) menadiol sodium disulfate.
Wikidata facts
- Mass
- 174.068
Show 3 more facts
- chemical formula
- C₁₁H₁₀O₂
- canonical SMILES
- CC1=C(C2=CC=CC=C2C(=C1)O)O
- Commons category
- Menadiol
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Menadiol is an organic compound with the formula C6H4(COH)2(CH)(CH3). It is formally the p-hydroquinone derivative of 2-methylnaphthalene. The name vitamin K4 can refer to: specifically this compound, its various esters, e.g. menadiol diacetate (acetomenaphthone), menadiol dibutyrate, menadiol dimalonate, or its various salts, like menadiol sodium diphosphate (Kappadione) menadiol sodium disulfate.
Menadiol sodium diphosphate is approved in the UK for treatment and prevention of haemorrhage, mainly in obstructive jaundice (before and after surgery). Unlike natural, lipophilic forms of vitamin K, menadiol sodium diphosphate does not require bile for absorption, hence the use in obstructive jaundice. A disadvantage is that it takes 24 hours to show effects, though the effects do last for several days. It can cause hemolytic anemia, more commonly in people with glucose 6-phosphate dehydrogenase deficiency or vitamin E deficiency.
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