File:Heparin_1.jpg · Wikimedia Commons · See Wikimedia Commons
heparin
Sign in to saveAlso known as Calciparine, Heparinic acid, Liquaemin, Heparinate, Hep-lock, Panheprin, Sodium heparin, heparin sodium
Heparin, also known as unfractionated heparin (UFH), is a medication and naturally occurring glycosaminoglycan. It is one of the most studied sulfated polysaccharides.
Heparin is a naturally occurring substance in the body that has been developed into an important medication, primarily used to prevent blood clots. It's one of the most thoroughly researched sulfated polysaccharides and remains widely studied in medical science.
AI-generated from the Wikipedia summary — may contain errors.
Research
120,084 papers- Heparin and anticoagulation.ReviewFrontiers in bioscience (Landmark edition) · 2016Onishi A, St Ange K, Dordick JS et al.DOI: 10.2741/4462
- Heparin: An old drug for new clinical applications.ReviewCarbohydrate polymers · 2022Wang P, Chi L, Zhang Z et al.DOI: 10.1016/j.carbpol.2022.119818
- Pharmacology of Heparin and Related Drugs: An Update.ReviewPharmacological reviews · 2023Hogwood J, Mulloy B, Lever R et al.DOI: 10.1124/pharmrev.122.000684
- The Anticoagulant and Nonanticoagulant Properties of Heparin.ReviewThrombosis and haemostasis · 2020Beurskens DMH, Huckriede JP, Schrijver R et al.DOI: 10.1055/s-0040-1715460
- The anti-cancer properties of heparin and its derivatives: a review and prospect.ReviewCell adhesion & migration · 2020Ma SN, Mao ZX, Wu Y et al.DOI: 10.1080/19336918.2020.1767489
- Heparin: role in protein purification and substitution with animal-component free material.ReviewApplied microbiology and biotechnology · 2018Bolten SN, Rinas U, Scheper TDOI: 10.1007/s00253-018-9263-3
- Nanosensor based approaches for quantitative detection of heparin.ReviewTalanta · 2024Pathak A, Verma N, Tripathi S et al.DOI: 10.1016/j.talanta.2024.125873
- Clinical guidance for unfractionated heparin dosing and monitoring in critically ill patients.ReviewExpert opinion on pharmacotherapy · 2024Samimi MN, Hale A, Schults J et al.DOI: 10.1080/14656566.2024.2364057
via PubMed
Wikidata facts
- Image
- Heparin Sodium sample.jpg
Show 3 more facts
- Commons category
- Heparins
- World Health Organisation international non-proprietary name
- heparin sodium
- chemical formula
- C₂₆H₄₁NO₃₄S₄
Sources (7)
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Article
28 sectionsContents
- History
- Medical use
- Adverse effects
- Contraindications
- Antidote to heparin
- Physiological function
- Evolutionary conservation
- Pharmacology
- Mechanism of action<!--LMWH links here-->
- Administration
- Natural degradation or clearance
- Chemistry
- Heparin structure
- Three-dimensional structure
- Depolymerization techniques
- Enzymatic
- Chemical
- Detection in body fluids
- Society and culture
- Contamination recalls
- 2008 recall due to adulteration in drug from China
- Use in homicide
- Overdose issues
- Production
- Research
- References
- Further reading
- External links
Heparin, also known as unfractionated heparin (UFH), is a medication and naturally occurring glycosaminoglycan. It is one of the most studied sulfated polysaccharides.
Heparin is a blood anticoagulant that increases the activity of antithrombin. It is used in the treatment of heart attacks and unstable angina. It can be given intravenously or by injection under the skin. Its anticoagulant properties make it useful to prevent blood clotting in blood specimen test tubes and kidney dialysis machines.