glycosaminoglycan
Sign in to saveAlso known as GAGs, glycosaminoglycans
class=skin-invert-image|thumb|240px|right|The repeating disaccharide unit (GlcUA(1β→3)GalNAc(1β→4))n of chondroitin sulfate. For polysaccharide nomenclature see here. R1, R2, R3 may have different values. Glycosaminoglycans (GAGs) or mucopolysaccharides are long, linear polysaccharides consisting of repeating disaccharide units (i.e., two-sugar units). The repeating two-sugar unit consists of a uronic sugar and an amino sugar, except in the case of the sulfated glycosaminoglycan keratan, where, in place of the uronic sugar there is a galactose unit. GAGs are found in vertebrates, invertebrates
In the Vinony graph
Vinony's link graph records 692 inbound references to glycosaminoglycan, and connects out to hexose, hyaluronic acid and sulfation.
It is catalogued under the topic Glycosaminoglycans.
Vinony links it to 31 Wikipedia language editions.
Research
146,852 papers- Glycosaminoglycan interaction networks and databases.Current opinion in structural biology · 2022
- Modeling glycosaminoglycan-protein complexes.Current opinion in structural biology · 2022
- Microbial glycosaminoglycan glycosyltransferases.Glycobiology · 2002
- Editorial: Proteoglycans and Glycosaminoglycan Modification in Immune Regulation and Inflammation.Frontiers in immunology · 2020
- The molecular mechanisms of glycosaminoglycan biosynthesis regulating chondrogenesis and endochondral ossification.Life sciences · 2023
via PubMed
Wikidata facts
- Has part
- amino sugar
Show 2 more facts
- Commons category
- Glycosaminoglycans
- topic's main category
- Category:Glycosaminoglycans
via Wikidata · CC0
~15 min read
Encyclopedic overview
10 sectionsContents
- Production
- HSGAG and CSGAG
- Keratan sulfate types
- Hyaluronic acid class
- Pharmacodynamics
- Classification
- Abbreviations
- See also
- References
- External links
class=skin-invert-image|thumb|240px|right|The repeating disaccharide unit (GlcUA(1β→3)GalNAc(1β→4))n of chondroitin sulfate. For polysaccharide nomenclature see here. R1, R2, R3 may have different values. Glycosaminoglycans (GAGs) or mucopolysaccharides are long, linear polysaccharides consisting of repeating disaccharide units (i.e., two-sugar units). The repeating two-sugar unit consists of a uronic sugar and an amino sugar, except in the case of the sulfated glycosaminoglycan keratan, where, in place of the uronic sugar there is a galactose unit. GAGs are found in vertebrates, invertebrates and bacteria. Because GAGs are highly polar molecules and attract water; the body uses them as lubricants or shock absorbers.
Mucopolysaccharidoses are a group of metabolic disorders in which abnormal accumulations of glycosaminoglycans occur due to enzyme deficiencies.
Excerpted from Wikipedia’s “glycosaminoglycan” article, available under the CC BY-SA 4.0 licence.