English
Structure via PubChem · Public domain (PubChem)
In the Vinony graph
Within Vinony's link graph, carboquone is referenced by 271 other articles, and connects out to tiazofurin, medication and drug.
It is catalogued under topics including 1,4-Benzoquinones, 1-Aziridinyl compounds and Alkylating antineoplastic agents.
Its subject is documented across 8 Wikipedia language editions.
Chemical data
- Formula
- C15H19N3O5
- Molecular weight
- 321.33 g/mol
- IUPAC name
- [2-[2,5-bis(aziridin-1-yl)-4-methyl-3,6-dioxocyclohexa-1,4-dien-1-yl]-2-methoxyethyl] carbamate
- SMILES
- CC1=C(C(=O)C(=C(C1=O)N2CC2)C(COC(=O)N)OC)N3CC3
- InChIKey
- SHHKQEUPHAENFK-UHFFFAOYSA-N
- XLogP
- -0.2
- Polar surface area
- 102 Ų
- H-bond donors
- 1
- H-bond acceptors
- 7
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
- Max clinical phase
- Phase 2
- Molecule type
- Small molecule
- Indications
- neoplasm
via ChEMBL · EBI
Research
276 papers- [An anticancer drug--carboquone].Gan to kagaku ryoho. Cancer & chemotherapy · 1988
- Carboquone therapy for hematologic neoplasms.The Tohoku journal of experimental medicine · 1982
- Treatment of multiple myeloma with carboquone-prednisolone.European journal of haematology · 1989
- Detection of DNA strand breaks in HeLa cells in vitro and in mouse sarcoma 180 cells in vivo induced by an alkylating agent, carboquone, using in situ nick translation.Oncology · 1990
- Interaction of antitumor agents including carboquone in sarcoma-180 system.Gan · 1976
via PubMed
Wikidata facts
- Subclass of
- chemical compound
- Mass
- 321.132
- Has use
- medication
Show 3 more facts
- chemical formula
- C₁₅H₁₉N₃O₅
- canonical SMILES
- CC1=C(C(=O)C(=C(C1=O)N2CC2)C(COC(=O)N)OC)N3CC3
- subject has role
- alkylating antineoplastic agent
Sources (2)
via Wikidata · CC0
~1 min read
Encyclopedic overview
2 sectionsContents
- References
- See also
{{Drugbox | Watchedfields = changed | verifiedrevid = 444188235 | IUPAC_name = {2-[2,5-bis(aziridin-1-yl)-4-methyl-3,6-dioxocyclohexa-1,4-dien-1-yl]-2-methoxyethyl} carbamate | image = Carboquone.png | image_class = skin-invert-image
| tradename = | pregnancy_AU = | pregnancy_US = | pregnancy_category = | legal_AU = | legal_CA = | legal_UK = | legal_US = | legal_status = | routes_of_administration =
Excerpted from Wikipedia’s “carboquone” article, available under the CC BY-SA 4.0 licence.
Available in 8 languages
via Wikidata sitelinks · CC0