Also known as CDD, cytidine deaminase
protein-coding gene in the species Homo sapiens
Gene data
CDA- Name
- cytidine deaminase
- Type
- protein-coding
- Position
- 20,588,932–20,618,908 (+)
- Aliases
- CDD
- Ensembl
- ENSG00000158825
- RefSeq RNA
- NM_001785.3
- RefSeq protein
- NP_001776.1
This gene encodes an enzyme involved in pyrimidine salvaging. The encoded protein forms a homotetramer that catalyzes the irreversible hydrolytic deamination of cytidine and deoxycytidine to uridine and deoxyuridine, respectively. It is one of several deaminases responsible for maintaining the cellular pyrimidine pool. Mutations in this gene are associated with decreased sensitivity to the cytosine nucleoside analogue cytosine arabinoside used in the treatment of certain childhood leukemias. [provided by RefSeq, Jul 2008].
Gene Ontology
Biological process
Molecular function
Pathways
via MyGene.info
Gene · Ensembl
cytidine deaminase
- Symbol
- CDA
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 1:20,588,898-20,618,913
- Strand
- Forward (+)
- Assembly
- GRCh38
View on Ensembl →
via Ensembl · EMBL-EBI
Wikidata facts
- Image
- Protein CDA PDB 1mq0.png
Show 5 more facts
- HomoloGene ID
- 1352
- exact match
- identifiers.org/ncbigene/978
- genomic end
- 20618903
- genomic start
- 20589086
- cytogenetic location
- 1p36.12
via Wikidata · CC0
Connections
activation induced cytidine deaminase
Protein
deoxyribonucleic acid
Entity
Q180686
Entity
Ensembl genome database project
Entity
enzyme
Entity
Wikidata
Entity
gene
Entity
chromosome
Entity
ribonucleic acid
Entity
digital object identifier
Entity
antibody
Entity
apoptotic process
Entity
bibcode
Entity
human genome
Entity
pyrimidine
Entity
Q229883
Entity
base pair
Entity
locus
Entity
gene expression
Entity
DNA repair
Entity