CDC37
Sign in to saveAlso known as P50CDC37, cell division cycle 37, cell division cycle 37, HSP90 cochaperone
Hsp90 co-chaperone Cdc37 is a protein that in humans is encoded by the CDC37 gene. This protein is highly similar to Cdc 37, a cell division cycle control protein of Saccharomyces cerevisiae. This protein is a HSP90 Co-chaperone with specific function in cell signal transduction. It has been shown to form complex with Hsp90 and a variety of protein kinases including CDK4, CDK6, SRC, RAF1, MOK, as well as eIF-2 alpha kinases. It is thought to play a critical role in directing Hsp90 to its target kinases.
Gene data
CDC37- Name
- cell division cycle 37, HSP90 cochaperone
- Type
- protein-coding
- Aliases
- P50CDC37
The protein encoded by this gene is highly similar to Cdc 37, a cell division cycle control protein of Sacchromyces cerevisiae. This protein is a molecular chaperone with specific function in cell signal transduction. It has been shown to form complex with Hsp90 and a variety of protein kinases including CDK4, CDK6, SRC, RAF-1, MOK, as well as eIF2 alpha kinases. It is thought to play a critical role in directing Hsp90 to its target kinases. [provided by RefSeq, Jul 2008].
via MyGene.info
Gene · Ensembl
cell division cycle 37, HSP90 cochaperone
- Symbol
- CDC37
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 19:10,391,090-10,420,224
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Image
- Protein CDC37 PDB 1us7.png
Show 5 more facts
- HomoloGene ID
- 38268
- exact match
- identifiers.org/ncbigene/11140
- genomic end
- 10530797
- genomic start
- 10391133
- cytogenetic location
- 19p13.2
via Wikidata · CC0
~1 min read
Article
5 sectionsContents
- Interactions
- Domain architecture
- References
- Further reading
- External links
Hsp90 co-chaperone Cdc37 is a protein that in humans is encoded by the CDC37 gene. This protein is highly similar to Cdc 37, a cell division cycle control protein of Saccharomyces cerevisiae. This protein is a HSP90 Co-chaperone with specific function in cell signal transduction. It has been shown to form complex with Hsp90 and a variety of protein kinases including CDK4, CDK6, SRC, RAF1, MOK, as well as eIF-2 alpha kinases. It is thought to play a critical role in directing Hsp90 to its target kinases.
== Interactions ==