IKBKB
Sign in to saveAlso known as IKK-beta, IKK2, IKKB, IMD15, NFKBIKB, inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta, inhibitor of nuclear factor kappa B kinase subunit beta, IMD15A
IKK-β also known as inhibitor of nuclear factor kappa-B kinase subunit beta is a protein that in humans is encoded by the IKBKB (inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta) gene.
Gene data
IKBKB- Name
- inhibitor of nuclear factor kappa B kinase subunit beta
- Type
- protein-coding
- Aliases
- IKK-2, IKK-beta, IKK2, IKKB, IMD15, IMD15A, IMD15B, NFKBIKB
The protein encoded by this gene phosphorylates the inhibitor in the inhibitor/NF-kappa-B complex, causing dissociation of the inhibitor and activation of NF-kappa-B. The encoded protein itself is found in a complex of proteins. Several transcript variants, some protein-coding and some not, have been found for this gene. [provided by RefSeq, Sep 2011].
via MyGene.info
Gene · Ensembl
inhibitor of nuclear factor kappa B kinase subunit beta
- Symbol
- IKBKB
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 8:42,271,302-42,332,460
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Image
- Protein IKBKB PDB 3BRT.png
Show 5 more facts
- HomoloGene ID
- 7782
- exact match
- identifiers.org/ncbigene/3551
- genomic end
- 42332460
- genomic start
- 42128820
- cytogenetic location
- 8p11.21
via Wikidata · CC0
~2 min read
Article
5 sectionsContents
- Function
- Clinical significance
- Interactions
- References
- See also
IKK-β also known as inhibitor of nuclear factor kappa-B kinase subunit beta is a protein that in humans is encoded by the IKBKB (inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta) gene.
== Function ==