CDC40
Sign in to saveAlso known as EHB3, PRP17, PRPF17, cell division cycle 40, PCH15
Pre-mRNA-processing factor 17 is a protein that in humans is encoded by the CDC40 gene.
In the Vinony graph
Within Vinony's link graph, CDC40 is referenced by 3 other articles, and connects out to PubMed, human chromosome 6 and Ensembl genome database project.
It is catalogued under the topic Genes on human chromosome 6.
Its subject is documented across 6 Wikipedia language editions.
Gene data
CDC40- Name
- cell division cycle 40
- Type
- protein-coding
- Position
- 110,180,141–110,254,275 (+)
- Aliases
- EHB3, PCH15, PRP17, PRPF17
- Ensembl
- ENSG00000168438
- RefSeq RNA
- NM_015891.3, XM_047418862.1, XM_054355580.1, XM_054355581.1
- RefSeq protein
- NP_056975.1, XP_047274818.1, XP_054211555.1, XP_054211556.1
Pre-mRNA splicing occurs in two sequential transesterification steps. The protein encoded by this gene is found to be essential for the catalytic step II in pre-mRNA splicing process. It is found in the spliceosome, and contains seven WD repeats, which function in protein-protein interactions. This protein has a sequence similarity to yeast Prp17 protein, which functions in two different cellular processes: pre-mRNA splicing and cell cycle progression. It suggests that this protein may play a role in cell cycle progression. [provided by RefSeq, Jul 2008].
Gene Ontology
Biological process
Molecular function
Pathways
via MyGene.info
Gene · Ensembl
cell division cycle 40
- Symbol
- CDC40
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 6:110,180,141-110,254,275
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
Show 7 more facts
- HomoloGene ID
- 5716
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/51362
- chromosome
- human chromosome 6
- genomic start
- 110501344
- genomic end
- 110575478
- cytogenetic location
- 6q21
Sources (4)
via Wikidata · CC0
~1 min read
Encyclopedic overview
3 sectionsContents
- References
- External links
- Further reading
Pre-mRNA-processing factor 17 is a protein that in humans is encoded by the CDC40 gene.
Pre-mRNA splicing occurs in two sequential transesterification steps. The protein encoded by this gene is found to be essential for the catalytic step II in pre-mRNA splicing process. It is found in the spliceosome, and contains seven WD repeats, which function in protein-protein interactions. This protein has a sequence similarity to yeast Prp17 protein, which functions in two different cellular processes: pre-mRNA splicing and cell cycle progression. It suggests that this protein may play a role in cell cycle progression.
Excerpted from Wikipedia’s “CDC40” article, available under the CC BY-SA 4.0 licence.