CDC73

Also known as C1orf28, FIHP, HPTJT, HRPT1, HRPT2, HYX, cell division cycle 73

Cell division cycle 73, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae), also known as CDC73 and parafibromin, is a protein which in humans is encoded by the CDC73 gene.

Gene data

CDC73

Name: cell division cycle 73
Type: protein-coding
Aliases: C1orf28, FIHP, HPTJT, HRPT1, HRPT2, HYX

This gene encodes a tumor suppressor that is involved in transcriptional and post-transcriptional control pathways. The protein is a component of the the PAF protein complex, which associates with the RNA polymerase II subunit POLR2A and with a histone methyltransferase complex. This protein appears to facilitate the association of 3' mRNA processing factors with actively-transcribed chromatin. Mutations in this gene have been linked to hyperparathyroidism-jaw tumor syndrome, familial isolated hyperparathyroidism, and parathyroid carcinoma. [provided by RefSeq, Jul 2009].

via MyGene.info

Gene · Ensembl

cell division cycle 73

Symbol: CDC73
Biotype: Protein coding
Organism: Homo sapiens
Location: 1:193,115,732-193,264,613
Strand: Forward (+)
Assembly: GRCh38

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via Ensembl · EMBL-EBI

Wikidata facts

Show 5 more facts

HomoloGene ID: 11571
exact match: identifiers.org/ncbigene/79577
genomic end: 193254815
genomic start: 193121983
cytogenetic location: 1q31.2

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via Wikidata · CC0

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Article

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Contents

Function
Clinical significance
See also
References
External links
Further reading

Cell division cycle 73, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae), also known as CDC73 and parafibromin, is a protein which in humans is encoded by the CDC73 gene.

==Function==