CDC73
Sign in to saveAlso known as C1orf28, FIHP, HPTJT, HRPT1, HRPT2, HYX, cell division cycle 73
gene umano
Gene data
CDC73- Name
- cell division cycle 73
- Type
- protein-coding
- Position
- 193,115,732–193,264,613 (+)
- Aliases
- C1orf28, FIHP, HPTJT, HRPT1, HRPT2, HYX
- Ensembl
- ENSG00000134371
- RefSeq RNA
- NM_024529.5, XM_006711537.5, XM_054338731.1
- RefSeq protein
- NP_078805.3, XP_006711600.1, XP_054194706.1
This gene encodes a tumor suppressor that is involved in transcriptional and post-transcriptional control pathways. The protein is a component of the the PAF protein complex, which associates with the RNA polymerase II subunit POLR2A and with a histone methyltransferase complex. This protein appears to facilitate the association of 3' mRNA processing factors with actively-transcribed chromatin. Mutations in this gene have been linked to hyperparathyroidism-jaw tumor syndrome, familial isolated hyperparathyroidism, and parathyroid carcinoma. [provided by RefSeq, Jul 2009].
Gene Ontology
Biological process
Pathways
via MyGene.info
Gene · Ensembl
cell division cycle 73
- Symbol
- CDC73
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 1:193,115,732-193,264,613
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
Show 8 more facts
- HomoloGene ID
- 11571
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/79577
- genomic end
- 193254815
- genomic start
- 193121983
- chromosome
- human chromosome 1
- cytogenetic location
- 1q31.2
- expressed in
- right ventricle
via Wikidata · CC0