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EntityQ21011233· pop 8· linked from 227 articles

Also known as LDK378, NVP-LDK378-NX, N-{2-[(5-chloro-2-{[2-isopropoxy-5-methyl-4-(piperidin-4-yl)phenyl]amino}pyrimidin-4-yl)amino]phenyl}propane-2-sulfonamide, compound 15b

Ceritinib (INN, trade name Zykadia ) is a prescription-only drug used for the treatment of non-small cell lung cancer (NSCLC). It was developed by Novartis and received FDA approval for use in April 2014.

Research

804 papers

via PubMed

~7 min read

Encyclopedic overview

12 sections
Contents
  • Medical uses
  • Adverse effects
  • Interactions
  • Pharmacology
  • Mechanism of action
  • Research and development
  • Society and culture
  • Economics
  • Intellectual property
  • Brand names
  • References
  • External links

{{Infobox drug | image = Ceritinib structure.svg | image_class = skin-invert-image | width = 275 | alt = | caption =

| pronounce = | tradename = Zykadia, others | Drugs.com = | MedlinePlus = a614027 | DailyMedID = Ceritinib | pregnancy_AU = | pregnancy_category = | routes_of_administration = By mouth | ATC_prefix = L01 | ATC_suffix = ED02

Excerpted from Wikipedia’s “ceritinib” article, available under the CC BY-SA 4.0 licence.

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