chills
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Chills is a feeling of coldness occurring during a high fever, but sometimes is also a common symptom which occurs alone in specific people. It occurs during fever due to the release of cytokines and prostaglandins as part of the inflammatory response, which increases the set point for body temperature in the hypothalamus. The increased set point causes the body temperature to rise (pyrexia), but also makes the patient feel cold or chills until the new set point is reached. Shivering also occurs along with chills because the patient's body produces heat during muscle contraction in a physiolog
Key facts
- Medical condition (new).name
- Chills
- Medical condition (new).field
- Infectious disease
via Wikipedia infobox
Research
17,414 papers- Utility of shaking chills as a diagnostic sign for bacteremia in adults: a systematic review and meta-analysis.BMC medicine · 2024
- Talimogene Laherparepvec Improves Durable Response Rate in Patients With Advanced Melanoma.Journal of clinical oncology : official journal of the American Society of Clinical Oncology · 2015
- Chills as an indicator of individual emotional peaks.Annals of the New York Academy of Sciences · 2009
- Understanding the symptoms of the common cold and influenza.The Lancet. Infectious diseases · 2005
- ChillsDB: A Gold Standard for Aesthetic Chills Stimuli.Scientific data · 2023
via PubMed
Wikidata facts
Show 3 more facts
- exact match
- purl.obolibrary.org/obo/SYMP_0019174
- ICPC 2 ID
- A02
- NCI Thesaurus ID
- C35143
Sources (8)
via Wikidata · CC0
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Article
4 sectionsContents
- Pathophysiology
- See also
- References
- External links
Chills is a feeling of coldness occurring during a high fever, but sometimes is also a common symptom which occurs alone in specific people. It occurs during fever due to the release of cytokines and prostaglandins as part of the inflammatory response, which increases the set point for body temperature in the hypothalamus. The increased set point causes the body temperature to rise (pyrexia), but also makes the patient feel cold or chills until the new set point is reached. Shivering also occurs along with chills because the patient's body produces heat during muscle contraction in a physiological attempt to increase body temperature to the new set point. When it does not accompany a high fever, it is normally a light chill.
Sometimes a chill of medium power and short duration may occur during a scare, especially in scares of fear, commonly interpreted like or confused by trembling.