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chlorfenvinphos

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Also known as chlorfenvinfos, Chlorfenvinfos, O,O-Diethyl-O-1-(2',4'-dichloro-phenyl)-2-chlorovinyl-phosphate, 2,4-Dichloro-alpha-(chloromethylene)benzyl diethyl phosphate

Chlorfenvinphos is an organophosphorus compound that was widely used as an insecticide and an acaricide. The molecule itself can be described as an enol ester derived from dichloroacetophenone and diethylphosphoric acid. Chlorfenvinphos has been included in many products since its first use in 1963. However, because of its toxic effect as a cholinesterase inhibitor it has been banned in several countries, including the United States and the European Union. Its use in the United States was discontinued in 1991.

~13 min read

Encyclopedic overview

16 sections
Contents
  • Pesticide use
  • History
  • Regulation and advisories
  • Production
  • Toxicokinetics
  • Mechanism of toxicity
  • Toxicity
  • Toxic effects
  • Acute toxicity
  • Long-term toxicity
  • Biomarkers
  • Biomarkers of exposure
  • Biomarkers of effect
  • Treatments of exposure
  • References
  • External links

Chlorfenvinphos is an organophosphorus compound that was widely used as an insecticide and an acaricide. The molecule itself can be described as an enol ester derived from dichloroacetophenone and diethylphosphoric acid. Chlorfenvinphos has been included in many products since its first use in 1963. However, because of its toxic effect as a cholinesterase inhibitor it has been banned in several countries, including the United States and the European Union. Its use in the United States was discontinued in 1991.

The pure chemical is a colorless solid, but for commercial purposes, it is often marketed as an amber liquid. The insecticides, mostly used in liquid form, contain between 50% and 90% chlorfenvinphos. The substance easily mixes with acetone, ethanol, and propylene glycol. Furthermore, chlorfenvinphos is corrosive to metal and hydrolyzes in the environment.

Excerpted from Wikipedia’s “chlorfenvinphos” article, available under the CC BY-SA 4.0 licence.