File:HCG_structure.png · Wikimedia Commons · See Wikimedia Commons
chorionic gonadotropin
Sign in to saveAlso known as Ovidrel, Atc Code G03 Ga Gonadotropins, Chorionic gonadotrophin beta subunit, Choriogonadotropin beta chain precursor, CG-beta, Choriogonadotropin alpha, hCG, human chorionic gonadotropin
human hormone
Key facts
- Symbol
- CGA
- Alt symbols
- FSHA, GPHa, GPHA1, HCG, LHA, TSHA
- Refseq
- NM_000735
- Uniprot
- P01215
- Locus
- Chr. 6 q14-q21
- Structures
- Swiss-model
- Domains
- InterPro
via Wikipedia infobox
Chemical data
Drug data · ChEMBL
- Max clinical phase
- Approved
- Molecule type
- Protein
- First approval
- 2000
- Admin. routes
- parenteral
- Indications
- infertility, polycystic ovary syndrome, obesity, primary ovarian insufficiency
via ChEMBL · EBI
Wikidata facts
- Subclass of
- polypeptide
- Has use
- medication
Show 5 more facts
- found in taxon
- Homo sapiens
- defined daily dose
- 0.25
- medical condition treated
- infertility
- Commons category
- Human chorionic gonadotropin
- has characteristic
- biopharmaceutical
via Wikidata · CC0
~23 min read
Encyclopedic overview
Human chorionic gonadotropin (hCG) is a hormone for the maternal recognition of pregnancy produced by trophoblast cells that are surrounding a growing embryo (syncytiotrophoblast initially), which eventually forms the placenta after implantation. The presence of hCG is detected in some pregnancy tests (HCG pregnancy strip tests). Some cancerous tumors produce this hormone; therefore, elevated levels measured when the patient is not pregnant may lead to a diagnosis of cancer and, if high enough, of paraneoplastic syndromes. It is unknown however whether this production is a contributing cause or an effect of carcinogenesis. The pituitary analogue of hCG, luteinizing hormone (LH), is produced in the pituitary gland of males and females of all ages.
Beta-hCG is initially secreted by the syncytiotrophoblast.
Excerpted from Wikipedia’s “chorionic gonadotropin” article, available under the CC BY-SA 4.0 licence.