cilastatin

Also known as MK 0791, (Z)-(S)-6-carboxy-6-[(S)-2,2-dimethylcyclopropanecarboxamido]hex-5-enyl-L-cysteine, (Z)-7-[(R)-2-amino-2-carboxy-ethylsulfanyl]-2-{[(S)-2,2-dimethyl-cyclopropanecarbonyl]-amino}-hept-2-enoic acid, (L)-7-(2-amino-2-carboxy-ethylsulfanyl)-2-[(2,2-dimethyl-cyclopropanecarbonyl)-amino]-hept-2-enoic acid

Cilastatin inhibits the human enzyme dehydropeptidase.

Research

2,028 papers

via PubMed

Wikidata facts

Mass: 358.156243

Show 5 more facts

chemical formula: C₁₆H₂₆N₂O₅S
World Health Organisation international non-proprietary name: cilastatin
isomeric SMILES: CC1(C[C@@H]1C(=O)N/C(=C\CCCCSC[C@@H](C(=O)O)N)/C(=O)O)C
canonical SMILES: CC1(CC1C(=O)NC(=CCCCCSCC(C(=O)O)N)C(=O)O)C
Commons category: Cilastatin

Sources (3)

via Wikidata · CC0

~3 min read

Article

2 sections

Contents

Uses
References

{{Drugbox | Watchedfields = changed | verifiedrevid = 460036539 | IUPAC_name = (Z)-7-[(2R)-2-Amino-3-hydroxy-3-oxopropyl]sulfanyl-2-{[(1S)-2,2-dimethylcyclopropanecarbonyl]amino}hept-2-enoic acid | image = Cilastatin.svg | image_class = skin-invert-image | width = 200 | alt = | image2 = Cilastatin ball-and-stick.png | image_class2 = bg-transparent | alt2 =