Also known as MK 0791, (Z)-(S)-6-carboxy-6-[(S)-2,2-dimethylcyclopropanecarboxamido]hex-5-enyl-L-cysteine, (Z)-7-[(R)-2-amino-2-carboxy-ethylsulfanyl]-2-{[(S)-2,2-dimethyl-cyclopropanecarbonyl]-amino}-hept-2-enoic acid, (L)-7-(2-amino-2-carboxy-ethylsulfanyl)-2-[(2,2-dimethyl-cyclopropanecarbonyl)-amino]-hept-2-enoic acid
Cilastatin inhibits the human enzyme dehydropeptidase.
via PubMed
{{Drugbox | Watchedfields = changed | verifiedrevid = 460036539 | IUPAC_name = (Z)-7-[(2R)-2-Amino-3-hydroxy-3-oxopropyl]sulfanyl-2-{[(1S)-2,2-dimethylcyclopropanecarbonyl]amino}hept-2-enoic acid | image = Cilastatin.svg | image_class = skin-invert-image | width = 200 | alt = | image2 = Cilastatin ball-and-stick.png | image_class2 = bg-transparent | alt2 =
| tradename = | Drugs.com = | MedlinePlus = a686013 | pregnancy_AU = | pregnancy_category = | routes_of_administration = Intravenous | ATC_prefix = J01 | ATC_suffix = DH51 | ATC_supplemental = (combination with imipenem)
via Wikidata sitelinks · CC0
Discovered by embedding cosine similarity (sentence-transformers MiniLM, 384-dim).