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GeneQ14913409· pop 6· linked from 111 articles

Also known as entrez:4056, Leukotriene C4 synthase

protein-coding gene in the species Homo sapiens

Gene data

LTC4S
Name
leukotriene C4 synthase
Type
protein-coding

The MAPEG (Membrane Associated Proteins in Eicosanoid and Glutathione metabolism) family includes a number of human proteins, several of which are involved the production of leukotrienes. This gene encodes an enzyme that catalyzes the first step in the biosynthesis of cysteinyl leukotrienes, potent biological compounds derived from arachidonic acid. Leukotrienes have been implicated as mediators of anaphylaxis and inflammatory conditions such as human bronchial asthma. This protein localizes to the nuclear envelope and adjacent endoplasmic reticulum. [provided by RefSeq, Jul 2008].

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Gene · Ensembl

leukotriene C4 synthase

Symbol
LTC4S
Biotype
Protein coding
Organism
Homo sapiens
Location
Chr HG30_PATCH:559,557-562,224
Strand
Forward (+)
Assembly
GRCh38
View on Ensembl →

via Ensembl · EMBL-EBI

Wikidata facts

Image
Protein LTC4S PDB 2PNO.png
Show 5 more facts
HomoloGene ID
7406
genomic start
179220981
genomic end
179223648
cytogenetic location
5q35.3
Sources (4)

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